This workstream focuses on how physical and mental health and wellbeing evolve throughout the various stages of life, focusing on the factors that influence the ultimate health and wellbeing outcomes of individuals. Understanding the role of modifiable factors and the impact of the broader determinants of health is of paramount importance to reduce health inequalities and to increase life expectancy free from ill-health. Further, this will serve as a resource for regional, national, and international decision-makers and policy developers. This will serve as a catalyst for integrating ongoing research efforts within our University's diverse community of researchers to advance the knowledge of health and wellbeing across different life stages, fostering connections and facilitate the continuous advancement of our collective understanding of health and wellbeing, from birth to death.