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Event

22nd International Conference on Oxygen Binding and Sensing Proteins (O2BiP)

Tue 26 - Fri 29 Aug 25

09:00
Event speaker

Multiple Speakers
Event type

Conferences
Contact details

O2BiP Conference o2bip@essex.ac.uk
+44 (0) 1206 872119

We are pleased to invite you to the O2BiP 2025 conference, the 22nd edition of the series of meetings that have been organised on the topic of oxygen-binding and sensing proteins (O2BiP).

Following the spirit of previous O2BiP editions, the meeting aims to focus on recent advances on the relationships between structure, dynamics, and function of globins, and gas binding and sensing related heme-proteins, covering all levels of organisation from molecular to cellular to systemic and "in vivo" models.

Download the programme (.docx) Download the booklet (.PDF)

The meeting will bring together researchers at all stages of their careers actively working in the fields of biochemistry, biophysics, structural biology, physiology, genetics, and evolutionary biology. Accordingly, our aim is to provide a forum for the presentation of recent advances and progresses in these fields, to bring together complementary research areas, and to catalyse existing and new scientific cooperation among teams with distinct expertise.

Dates and times

26 August 2025: 4pm - 9pm
27 - 29 August 2025: 9am - 5.30pm

Book here to register your place

Preliminary Programme

View the programme below or download the Word document.

Tuesday 26 August 2025

Time	Event	Location
15:00 - 17:00	Registration	TBC
17:00 - 19:00	Welcome BBQ	Silberrad Centre Plazza

Wednesday 27 August 2025

Rooms: EBS 2.2, 2.65 & 2.66

Time	Event	Location	Speakers
08:30 - 17:00	Registration	Essex Business School
08:50 - 09:20	Tea and coffee available	EBS 2.65 & 2.66
09:20 - 09:30	Welcome	EBS 2.2	Dr Brandon Reeder
09:30 - 12:35	Session 1: Bacterial heme proteins and heme based sensors	EBS 2.2	Chairpersons: Angelo Fago, Dimitri Svistunenko
09:30 - 09:55	Anaerobic and aerobic sulfide binding to human neuroglobin: sulfheme derivatives	EBS 2.2	Federico Sebastiani, University of Florence
09:55 - 10:20	The high diversity of oxygen reactivity in bacterial terminal oxidases	EBS 2.2	Petra Hellwig, University of Strasbourg
10:20 - 10:45	From antibacterial strategy to modulation of hemoglobin oxygen affinity: the unexpected dual role of C35	EBS 2.2	Serena Faggiano, University of Parma
10:45 - 11:10	Anaerobic heme catabolism in three bacterial pathogens	EBS 2.2	Kirsten Wolthers, The University of British Columbia
11:10 - 11:40	Morning refreshments and poster session	EBS 2.65 & 2.66
11:40 - 12:05	Targeting aerobic respiratory chains to combat bacterial pathogens	EBS 2.2	Mark Shepherd, University of Kent
12:05 - 12:35	Abstract selected speakers:
12:05 - 12:20	The bd-type Cyanide Insensitive Oxidase from the multidrug-resistant pathogen Pseudomonas aeruginosa: interaction with gaseous ligands	EBS 2.2	Elena Forte, Sapienza University of Rome
12:20 - 12:35	Targeting cytochrome bd oxidases from Acinetobacter baumannii with steroid drugs	EBS 2.2	Guy Joiner, University of Kent
12:35 - 14:00	Lunch and poster session	EBS 2.65 & 2.66
14:00 - 17:20	Session 2: Evolution of oxygen binding proteins	EBS 2.2	Chairperson: Michael Berenbrink
14:00 - 14:25	Conformational analysis of human and crocodilian Hb by cryo-electron microscopy	EBS 2.2	Jeremy Tame, Yokohama City University
14:25 - 14:50	Ngb function in Zebrafish – lessons learned from a knockout model	EBS 2.2	Andrej Fabrizius, University of Hamburg
14:50 - 15:15	Convergent reductions in hemoglobin buffering power in lineages of small, high-metabolic rate birds and mammals: implications for O2 delivery	EBS 2.2	Kevin Campbell, University of Iowa
15:15 - 15:40	Convergent evolution of Hb/Mb function in diving/high metabolic rate birds and mammals	EBS 2.2	Michael Berenbrink, University of Liverpool
15:40 - 16:10	Afternoon refreshments and poster session	EBS 2.65 & 2.66
16:10 - 17:20	Abstract selected speakers:
16:10 - 16:25	Characterization of bryophyte hemoglobins provides insight into ancestral functions	EBS 2.2	Ryan Sturms, Drake University
16:25 - 16:40	The Role of Globin Proteins in the Transition from Water to Land	EBS 2.2	Soraya Safavi, University of Hamburg
16:40 - 16:55	Resurrecting lost ancient myoglobins to elucidate mechanisms of diving adaptation in mammals	EBS 2.2	Hiroshi Imamura, Nagahama Institute of Bio-Science and Technology
18:00 - 19:30	Evening excursion to Colchester Castle

Thursday 28 August 2025

Rooms: EBS 2.2, 2.65 & 2.66

Time	Event	Location	Speakers
08:50 - 09:20	Tea and coffee	EBS 2.65 & 2.66
09:20 - 13:00	Session 3: Structure, function and dynamics	EBS 2.2	Chairpersons: Mark Shepherd, Luca Ronda
09:20 - 09:45	Phytoglobins - some new insights into their structure and biological function	EBS 2.2	Leif Bulow, Lund University
09:45 - 10:10	Heme-based dioxygenases: Structure, function and dynamics	EBS 2.2	Syun-Ru Yeh, Albert Einstein College of Medicine
10:10 - 10:35	Structural insights into the functional properties of cytochrome c oxidase	EBS 2.2	Denis Rousseau, Albert Einstein College of Medicine
10:35 - 11:00	Cytochrome b5 reductase 4 efficiently reduces Neuroglobin and Cytoglobin	EBS 2.2	Jesús Tejero, University of Pittsburgh
11:00 - 11:30	Morning refreshments and poster session	EBS 2.65 & 2.66
11:30 - 11:55	Role of haemoglobin in mixed biofilm formation	EBS 2.2	Campbell Gourlay, University of Kent
11:55 - 12:55	Abstract selected speakers:
11:55 - 12:10	The multiplicity of the Caenorhabditis elegans globin family	EBS 2.2	Bart Braeckman, Ghent University
12:10 - 12:25	The enhanced hemoglobin function can be explained by additional tertiary structural changes exerted by changes in hydrophobicity in the α1β1 interface	EBS 2.2	Antonio Tsuneshige, Hosei University
12:25 - 12:40	Characterization of globin Y in vertebrates	EBS 2.2	Cäcilia Plate, University of Hamburg
12:40 - 12:55	Hemoglobin haem capture by staphylococcal receptor IsdB: a complex process unveiled by time-resolved X-ray solution scattering	EBS 2.2	Marialaura Marchetti, University of Hamburg
12:55 - 13:50	Lunch and poster session	EBS 2.65 & 2.66
13:50 - 17:20	Session 4: Heme-proteins in health and diseases	EBS 2.2	Chairpersons: David Hoogewijs, Brandon Reeder
13:50 - 14:15	Cytoglobin in Hepatic Stellate Cells Plays an Anti-fibrotic Role in Chronic Liver Injury	EBS 2.2	Norifumi Kawada, Osaka Metropolitan University
14:15 - 14:40	Targeting Nitric Oxide-Driven Cancer Progression: Hemin Derivatives Suppress Migration and Angiogenesis via Redox Pathway Modulation	EBS 2.2	Amir Abdo, University of Galway
14:40 - 15:05	Androglobin in basal metazoans: ancient functional association with cilia	EBS 2.2	Carina Osterhof, University of Fribourg
15:05 - 15:30	Cytoglobin controls cardiac morphogenesis by regulating NO-sGC signaling	EBS 2.2	Paola Corti, University of Maryland
15:30 - 16:00	Afternoon refreshments and poster session	EBS 2.65 & 2.66
16:00 - 16:25	Cytoglobin as a mediator of non-canonical redox signaling	EBS 2.2	Jian Cui
16:25 - 17:35	Abstract selected speakers:
16:25 - 16:40	Neuroglobin and Cytoglobin – Investigation of Functional role in the retina	EBS 2.2	Ranjan Rajendram, University College London
16:40 - 17:15	Cytoglobin: A potential respiratory regulator in retinal cells	EBS 2.2	Alex Binderup Sort Jensen, Aarhus University
17:15 - 17:30	Heme Modulation of p53 and p63: Structural and Functional Insights	EBS 2.2	Artur Sergunin, Charles University
19:30 - 21:30	Dinner at Wivenhoe House	Wivenhoe House Hotel

Friday 29 August 2025

Rooms: EBS 2.2, 2.65 & 2.66

Time	Event	Location	Speakers
09:00 - 09:20	Tea and coffee	EBS 2.65 & 2.66
09:20 - 13:00	Session 5: Emerging topics in oxygen binding/sensing proteins	EBS 2.2	Chairperson: Stefano Bruno, Mike Wilson
09:20 - 09:45	Illuminating Heme Loss from Hemoglobin: New Fluorescent Tools to Track Heme-Iron Flow During Infection	EBS 2.2	Robert Clubb, University of California
09:45 - 10:10	HBOCs for Ex Vivo Kidney Reconditioning: Biocompatibility, Microbial Control, and Functional Assessment	EBS 2.2	Stefano Bruno, University of Parma
10:10 - 10:35	Engineering heme stability in recombinant hemoglobin for the development of a prototype for stable hemoglobin based oxygen carrier	EBS 2.2	Suman Kundu, University of Delhi
10:35 - 11:00	Reengineering hemoglobin for safer synthetic oxygen therapeutics	EBS 2.2	Brandon Reeder, University of Essex
11:00 - 11:30	Morning refreshments and poster session	EBS 2.65 & 2.66
11:30 - 11:50	Molecular oxygen activation in the cofactor-less formyl glycine generating enzyme investigated using dose-resolved X-ray crystallography	EBS 2.2	Marina Lucic, University of Essex
11:50 - 12:15	Remembering Professor Andrea Mozzarelli: A Life in Structure, Dynamics, and Function of Protein	EBS 2.2	Luca Ronda, University of Parma
11:50 - 12:35	Abstract selected speakers:
11:50 - 12:05	CRISPR/Cas9-mediated knockouts of globins 1, 2 and 3 in Drosophila melanogaster	EBS 2.2	Ruben Petry, Johannes Gutenberg University Mainz
12:05 - 12:20	Mapping myoglobin expression in epithelial tissues using a cross-tissue single-cell atlas	EBS 2.2	Michelle Hagmaier, Johannes Gutenberg University Mainz
12:20 - 12:35	Multi-Omics Analysis of Myoglobin Knockout Zebrafish Metabolism	EBS 2.2	Ciska Bakkeren, Aarhus University
12:35 - 13:30	Closing remarks and poster/oral presentation prizes	EBS 2.2
13:30	Conference closes
14:00 - 16:00	Practical workshop: Biophysical Methods for Studying Oxygen-Binding Heme Proteins (Limited numbers, sign-up sheet at registration desk or EBS 2.65)

Registration Information

The registration fees include the following:

access to all scientific sessions
poster sessions
refreshments during coffee/tea breaks and lunches.

Please note that the registration will only be valid AFTER receiving the registration form and copy of the bank transfer. The registration fees are non-refundable.

Type of attendee	Early Bird (Until July 25th)	Online Registration (GBP)
Senior	£350	£500
Post-Doc	£250	£400
PhD Student	£180	£320
Registered Accompanying Person(s)	£110	£110
1-Day only	£150	£150
Social dinner	£60	£75
Social dinner (not registered)	£75	N/A

PhD students and Post-Doc

Please send by email your student PhD card or other formal identification as proof of your student/PhD status or Post-Doc status

Registered Accompanying Persons(s)*

Registered accompanying persons may not be co-author of any oral or poster presentation, they have access to all symposia, oral and poster sessions, refreshments during coffee/tea breaks but will not receive an attendance certificate.

Please note: Only “Registered accompanying persons” will be allowed to accompany the speaker into the conference building/session.

Registration 1-Day only

For a limited number of people only, it is now available a flat 1-day only registration fee of £150.00. This is NOT valid for presenting authors.

This registration will allow you, for one day only (one date only), to attend both scientific and social events, including refreshments during coffee/tea breaks and excluding the Social Dinner.