People

Dr Na You

Senior Lecturer
School of Mathematics, Statistics and Actuarial Science (SMSAS)
Dr Na You
  • Email

  • Telephone

    +44 (0) 1206 873765

  • Location

    3A.536, Colchester Campus

Profile

Biography

Na You is a Senior Lecturer in Statistics at the Department of Mathematical Sciences of the University of Essex. Prior to joining the University of Essex in 2023, Dr. You was a Professor of Statistics at Sun Yat-sen University (Guangzhou) where she started as an Associate and worked for 12 years since 2011. Before that, she obtained her PhD degree from Peking University in 2005, and had a 5-year postdoc training at University of California, Riverside, USA. Dr. You is interested in the methodology research in Biostatistics and its applications in medical research, especially for (ultra-)high dimensional data analysis. Her research topics cover multiple testing, variable selection, mixture model and non-parametric statistics, for the identification of genomic biomarkers from (ultra-)high dimensional data, and the prediction of patient's prognosis. Recently, she focus on nonparametric testing, regression with non-Euclidean predictors, and their applications for treatment effect evaluation and image data analysis.

Qualifications

  • PhD Peking University, (2005)

  • BSc Yantai University, (2000)

Appointments

University of Essex

  • Senior Lecturer, Department of Mathematical Sciences, University of Essex (22/5/2023 - present)

Other academic

  • Professor, School of Mathematics, Sun Yat-sen University (10/4/2018 - 30/6/2023)

  • Associate Professor, School of Mathematics, Sun Yat-sen University (28/6/2011 - 10/4/2018)

Research and professional activities

Research interests

Statistical divergence for survival analysis

Nonparametric methodology development for the hypothesis testing of survival outcomes

Key words: Nonparameteric statistics
Open to supervise

Survival regression

Methodology development for survival prediction by incorporating non-Euclidean predictors such as the shape data

Key words: non-Euclidean data
Open to supervise

Teaching and supervision

Current teaching responsibilities

  • Databases and data processing with SQL (MA332)

  • Modelling experimental and observational data (MA335)

Publications

Journal articles (27)

You, N., Dai, H., Wang, X. and Yu, Q., (2024). Sequential estimation for mixture of regression models for heterogeneous population. Computational Statistics and Data Analysis. 194, 107942-107942

You, N., Xueyi, H., Dai, H. and Xueqin, W., (2023). Ball divergence for the equality test of crossing survival curves. Statistics in Medicine. 42 (29), 5353-5368

Chen, B., He, X., Pan, B., Zou, X. and You, N., (2021). Comparison of beta diversity measures in clustering the high-dimensional microbial data. PLOS ONE. 16 (2), e0246893-e0246893

Chen, B., You, N., Pan, B., He, X. and Zou, X., (2021). Application of Clustering Method to Explore the Correlation Between Dominant Flora and the Autism Spectrum Disorder Clinical Phenotype in Chinese Children. Frontiers in Neuroscience. 15, 760779-

Yang, W., You, N., Jia, M., Yeung, S-CJ., Ou, W., Yu, M., Wang, Y., Fu, X., Zhang, Z., Yang, J., Lao, Z., Liu, Z., Zeng, B., Ou, Q., Wu, X., Shao, YW., Hong, X., Wang, S. and Cheng, C., (2020). Undetectable circulating tumor DNA levels correlate with low risk of recurrence/metastasis in postoperative pathologic stage I lung adenocarcinoma patients. Lung Cancer. 146, 327-334

Tang, J., Zhang, C-B., Lyu, K-S., Jin, Z-M., Guan, S-X., You, N., Huang, M., Wang, X-D. and Gao, X., (2020). Association of polymorphisms in C1orf106, IL1RN, and IL10 with post-induction infliximab trough level in Crohn’s disease patients. Gastroenterology Report. 8 (5), 367-373

Zhong, W., Tan, L., Jiang, WG., Chen, K., You, N., Sanders, AJ., Liang, G., Liu, Z., Ling, Y. and Gong, C., (2019). Effect of younger age on survival outcomes in T1N0M0 breast cancer: A propensity score matching analysis. Journal of Surgical Oncology. 119 (8), 1039-1046

You, N., He, S., Wang, X., Zhu, J. and Zhang, H., (2018). Subtype Classification and Heterogeneous Prognosis Model Construction in Precision Medicine. Biometrics. 74 (3), 814-822

You, N. and Wang, X., (2017). An empirical Bayes method for robust variance estimation in detecting DEGs using microarray data. Journal of Bioinformatics and Computational Biology. 15 (05), 1750020-1750020

Wu, W., Deng, H., Rao, N., You, N., Yang, Y., Cao, M. and Liu, J., (2017). Neoadjuvant everolimus plus letrozole versus fluorouracil, epirubicin and cyclophosphamide for ER-positive, HER2-negative breast cancer: study protocol for a randomized pilot trial. Trials. 18 (1), 497-

Zhao, J., Wang, Y., Lao, Z., Liang, S., Hou, J., Yu, Y., Yao, H., You, N. and Chen, K., (2017). Prognostic immune-related gene models for breast cancer: a pooled analysis. OncoTargets and Therapy. Volume 10, 4423-4433

Liang, H., Xiang, Y-Q., Lv, X., Xie, C-Q., Cao, S-M., Wang, L., Qian, C-N., Yang, J., Ye, Y-F., Gan, F., Ke, L-R., Yu, Y-H., Liu, G-Y., Qiu, W-Z., Huang, X-J., Wen, C-H., You, N., Wang, X-Q., Guo, X. and Xia, W-X., (2017). Survival impact of waiting time for radical radiotherapy in nasopharyngeal carcinoma: A large institution-based cohort study from an endemic area. European Journal of Cancer. 73, 48-60

Wen, C-H., Ou, S-M., Guo, X-B., Liu, C-F., Shen, Y-B., You, N., Cai, W-H., Shen, W-J., Wang, X-Q. and Tan, H-Z., (2017). B-CAN: a resource sharing platform to improve the operation, visualization and integrated analysis of TCGA breast cancer data. Oncotarget. 8 (65), 108778-108785

Miller, ER., Cooper, LA., Carson, KA., Wang, N-Y., Appel, LJ., Gayles, D., Charleston, J., White, K., You, N., Weng, Y., Martin-Daniels, M., Bates-Hopkins, B., Robb, I., Franz, WK., Brown, EL., Halbert, JP., Albert, MC., Dalcin, AT. and Yeh, H-C., (2016). A Dietary Intervention in Urban African Americans. American Journal of Preventive Medicine. 50 (1), 87-95

Huang, G., Wang, S., Wang, X. and You, N., (2016). An empirical Bayes method for genotyping and SNP detection using multi-sample next-generation sequencing data. Bioinformatics. 32 (21), 3240-3245

Gong, C., Tan, W., Chen, K., You, N., Zhu, S., Liang, G., Xie, X., Li, Q., Zeng, Y., Ouyang, N., Li, Z., Zeng, M., Zhuang, S., Lau, W-Y., Liu, Q., Yin, D., Wang, X., Su, F. and Song, E., (2016). Prognostic Value of a BCSC-associated MicroRNA Signature in Hormone Receptor-Positive HER2-Negative Breast Cancer. EBioMedicine. 11, 199-209

Murillo, GH., You, N., Su, X., Cui, W., Reilly, MP., Li, M., Ning, K. and Cui, X., (2016). MultiGeMS: detection of SNVs from multiple samples using model selection on high-throughput sequencing data. Bioinformatics. 32 (10), 1486-1492

Ding, W., Kou, Q., Wang, X., Xu, Q. and You, N., (2015). Single-sample SNP detection by empirical Bayes method using next-generation sequencing data. Statistics and Its Interface. 8 (4), 457-462

You, N., Mou, P., Qiu, T., Kou, Q., Zhu, H., Chen, Y. and Wang, X., (2012). Gene Expression Network Reconstruction by LEP Method Using Microarray Data. The Scientific World Journal. 2012, 1-6

You, N., Murillo, G., Su, X., Zeng, X., Xu, J., Ning, K., Zhang, S., Zhu, J. and Cui, X., (2012). SNP calling using genotype model selection on high-throughput sequencing data. Bioinformatics. 28 (5), 643-650

Cui, X., You, N., Girke, T., Michelmore, R. and Van Deynze, A., (2010). Single feature polymorphism detection using recombinant inbred line microarray expression data. Bioinformatics. 26 (16), 1983-1989

Xuan Mao, C. and You, N., (2009). On Comparison of Mixture Models for Closed Population Capture–Recapture Studies. Biometrics. 65 (2), 547-553

You, N. and Mao, CX., (2009). On hierarchical loglinear models in capture–recapture studies. Computational Statistics & Data Analysis. 53 (12), 3916-3920

You, N., Liu, J. and Mao, CX., (2008). An Empirical Bayesian Method for Detecting Differentially Expressed Genes Using EST Data. International Journal of Plant Genomics. 2008, 1-4

You, N. and Xuan Mao, C., (2008). Population Size Estimation in a Two‐List Surveillance System with a Discrete Covariate. Biometrics. 64 (2), 371-376

Xu, Y., Liu, L., You, N., Pan, H. and Yip, P., (2007). Estimating Population Size for a Continuous Time Frailty Model with Covariates in a Capture–Recapture Study. Biometrics. 63 (3), 917-921

ZHANG, L., LIU, L. and YOU, NA., (2005). Estimating Population Size in Logistic Capture-Recapture Models with a Known Sex Ratio. Communications in Statistics - Theory and Methods. 34 (1), 37-44

Book chapters (1)

Mao, CX. and You, N., (2010). Estimate the initial population size from removal data. In: Biometrics: Methods, Applications and Analysis. 187- 195. 9781608764129

Contact

na.you@essex.ac.uk
+44 (0) 1206 873765

Location:

3A.536, Colchester Campus

More about me