New tools for time-resolved X-ray crystallography

  • Thu 21 Jan 21

    13:00 - 14:00

  • Online


  • Event speaker

    Dr Briony Yorke

  • Event type

    Lectures, talks and seminars

  • Event organiser

    Life Sciences, School of

  • Contact details

    Dr Mike Hough

Over the last 10 years, Time-resolved crystallography has entered a renaissance.

The development of free-electron lasers has allowed the ultrafast determination of structural changes occurring in important light sensitive systems such as photosystems 1 & 2, bacteriorhodopsin and photoactive yellow protein. However, many biological systems are not inherently photoactive and their functional dynamics occur on slower timescales from nanoseconds - seconds.

Our work focuses on the development of new techniques applicable to these systems using widely available synchrotron radiation, in order to allow time-resolved crystallography to become part of the standard structural biology toolkit.


Briony completed her MChem at the school of Chemistry, University of Leeds before starting a Wellcome Trust 4-year PhD at the Astbury Centre, University of Leeds (Dr. Arwen Pearson) and Diamond Light Source, UK (Dr. Robin Owen).

During the final year of her PhD she moved alongside Dr. Pearson to the centre for ultrafast imaging (CUI, Hamburg) where she was granted a Sir Henry Wellcome Post-Doctoral fellowship to develop Hadamard time-resolved crystallography to investigate the structural dynamics involved in the formation of cataracts. In 2020, Briony started a lectureship at the University of Bradford.

How to attend

Please register for this event on Zoom. If you have any queries email Dr Mike Hough (mahough@essex.ac.uk).

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