Genomic and metabolic regulation in proliferating and ageing cells of fission yeast

Speaker

Jürg Bähler completed his PhD at the University of Bern (Switzerland). After short stays as Research Associate in Japan and Switzerland, he worked as a Postdoctoral Fellow with John Pringle at the University of North Carolina (Chapel Hill, USA) and with Paul Nurse at Imperial Cancer Research Fund (London, UK). In 2000, Bähler joined the Wellcome Trust Sanger Institute (Hinxton, UK) as a Group Leader. In 2009, he was appointed as a Professor of Systems Biology at University College London and recently became the Director of UCL’s Institute of Healthy Ageing.

The Bähler laboratory studies cellular quiescence and ageing using fission yeast and the short-lived African turquoise killifish as model systems. They apply genetic, computational and genome-wide approaches for systems-level understanding of ageing-related processes and complex relationships between genotype, phenotype, and environment, including roles of energy metabolism, genome regulation and non-coding RNAs.