Postponed: Long non-coding mrhl and its role in gene regulation

Long non-coding RNAs (lncRNAs) are emerging as key regulators of diverse cellular functions with ongoing efforts focusing on understanding the mechanism of regulation.

LncRNA mrhl is a mouse transcript which plays a role in the negative regulation of Wnt signaling pathway and in turn, meiotic commitment in the spermatogonial cells. In addition to binding at distinct loci within the genome, mrhl has been shown to regulate a modest number of genes present close to its binding sites.

I will discuss my ongoing work towards elucidating the mechanism of gene regulation by mrhl.

Speaker

Bhavana Kayyar is a PhD student at the Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, and an EMBO Visiting Fellow.