The role of the bacterial metabolites sensors in the host-microbiota interactions

Recent studies indicate a prominent role of the intestinal microbiota in the regulation of physiological aspects including the development and activation of the immune system and the regulation of host metabolism.

Bacterial metabolites called short-chain fatty acids (SCFA) constitute a key mechanism of communication between microbiota and host cells and changes in their production are associated with inflammatory and metabolic diseases.

In this talk, Professor Vinolo will present and discuss recent results of our group indicating that strategies that change the intestinal levels of these molecules have beneficial effects in bacterial and viral infections. He will also discuss the molecular and cellular targets of SCFAs involved in these effects.

Speaker

Professor Marco Vinolo is a professor in the Institute of Biology, University of Campinas Brazil.