2013 - Laboratory Technician, University of Essex. Duties include maintaining laboratory health and safety, maintenance/repair of laboratory equipment, training of students in both health and safety and in basic laboratory techniques, supporting research groups as necessary.
2015 - Member of Dr Hough's research group, University of Essex. Researching Cytochrome c' structure and function
2016 - p/t PhD Biological Sciences, University of Essex.
The aim of this research is to elucidate the structure and function of the c-beta of Methylococcus capsulatus Bath (MCCP Bath) and to study its ability to bind to and discriminate between gaseous ligands in comparison to the more conventional four-alpha-helical cytochromes c. This research will also investigate the relationship with cytochrome P460, a protein which co-purifies with MCCP Bath. Cytochrome P460 was shown to have a good sequence homology with MCCP Bath along with a similar predicted highly beta sheet secondary structure which suggests an evolutionary history between the two proteins.
One fold, two functions: cytochrome P460 and cytochrome c'-ß from the methanotroph Methylococcus capsulatus (Bath) Chemical Science, 2019, DOI: 10.1039/C8SC05210G