Dr Metodi Metodiev

Waszczak, N., DeFlorio, R., Ismael, A., Cheng, N., Stone, DE. and Metodiev, MV., (2019). Quantitative proteomics reveals a Gα/MAPK signaling hub that controls pheromone-induced cellular polarization in yeast. Journal of Proteomics. 207, 103467-103467

Gregson, BH., Metodieva, G., Metodiev, MV., Golyshin, PN. and McKew, BA., (2018). Differential Protein Expression During Growth on Medium Versus Long-Chain Alkanes in the Obligate Marine Hydrocarbon-Degrading Bacterium Thalassolituus oleivorans MIL-1. Frontiers in Microbiology. 9, 3130-

Welbourn, EM., Wilson, MT., Yusof, A., Metodiev, MV. and Cooper, CE., (2017). The mechanism of formation, structure and physiological relevance of covalent hemoglobin attachment to the erythrocyte membrane. Free Radical Biology and Medicine. 103, 95-106

Todorova, K., Metodiev, MV., Metodieva, G., Mincheff, M., Fernández, N. and Hayrabedyan, S., (2017). Micro-RNA-204 Participates in TMPRSS2/ERG Regulation and Androgen Receptor Reprogramming in Prostate Cancer. Hormones and Cancer. 8 (1), 28-48

Harrod, A., Fulton, J., Nguyen, VTM., Periyasamy, M., Ramos-Garcia, L., Lai, C-F., Metodieva, G., de Giorgio, A., Williams, RL., Santos, DB., Gomez, PJ., Lin, M-L., Metodiev, MV., Stebbing, J., Castellano, L., Magnani, L., Coombes, RC., Buluwela, L. and Ali, S., (2017). Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer. Oncogene. 36 (16), 2286-2296

Mitchell, MC., Metodieva, G., Metodiev, M., Griffiths, H. and Meyer, MT., (2017). Pyrenoid loss impairs carbon-concentrating mechanism induction and alters primary metabolism in Chlamydomonas reinhardtii. Journal of Experimental Botany. 68 (14), 3891-3902

Hayrabedyan, S., Todorova, K., Jabeen, A., Metodieva, G., Toshkov, S., Metodiev, M., Mincheff, M. and Fern�ndez, N., (2016). Sertoli cells have a functional NALP3 inflammasome that can modulate autophagy and cytokine production. Scientific Reports. 6 (18896), 18896-

Metodieva, G., Adoki, S., Lausen, B. and Metodiev, MV., (2016). Decreased Usage of Specific Scrib Exons Defines a More Malignant Phenotype of Breast Cancer With Worsened Survival. EBioMedicine. 8, 150-158

Ismael, A., Tian, W., Waszczak, N., Wang, X., Cao, Y., Suchkov, D., Bar, E., Metodiev, M., Liang, J., Arkowitz, RA. and Stone, DE., (2016). Gβ promotes pheromone receptor polarization and yeast chemotropism by inhibiting receptor phosphorylation. Science Signaling. 9 (423), ra38-

Croner, R., Sevim, M., Metodiev, M., Jo, P., Ghadimi, M., Schellerer, V., Brunner, M., Geppert, C., Rau, T., Stürzl, M., Naschberger, E., Matzel, K., Hohenberger, W., Lottspeich, F. and Kellermann, J., (2016). Identification of Predictive Markers for Response to Neoadjuvant Chemoradiation in Rectal Carcinomas by Proteomic Isotope Coded Protein Label (ICPL) Analysis. International Journal of Molecular Sciences. 17 (2), 209-209

Todorova, K., Metodiev, MV., Metodieva, G., Zasheva, D., Mincheff, M. and Hayrabedyan, S., (2016). miR‐204 is dysregulated in metastatic prostate cancer in vitro. Molecular Carcinogenesis. 55 (2), 131-147

McKew, BA., Metodieva, G., Raines, CA., Metodiev, MV. and Geider, RJ., (2015). Acclimation of Emiliania huxleyi (1516) to nutrient limitation involves precise modification of the proteome to scavenge alternative sources of N and P. Environmental Microbiology. 17 (10), 4050-4062

Mock, T., Daines, SJ., Geider, RJ., Collins, S., Metodiev, M., Millar, AJ., Moulton, V. and Lenton, TM., (2015). Bridging the gap between omics and earth system science to better understand how environmental change impacts marine microbes. Global Change Biology. 22 (1), 61-75

Mahmoud, O., Harrison, A., Perperoglou, A., Gul, A., Khan, Z., Metodiev, MV. and Lausen, B., (2014). A feature selection method for classification within functional genomics experiments based on the proportional overlapping score. BMC Bioinformatics. 15 (1), 274-

Croner, RS., Stürzl, M., Rau, TT., Metodieva, G., Geppert, CI., Naschberger, E., Lausen, B. and Metodiev, MV., (2014). Quantitative proteome profiling of lymph node-positivevs. -negative colorectal carcinomas pinpoints MX1 as a marker for lymph node metastasis. International Journal of Cancer. 135 (12), 2878-2886

Mckew, BA., Lefebvre, SC., Achterberg, EP., Metodieva, G., Raines, CA., Metodiev, MV. and Geider, RJ., (2013). Plasticity in the proteome of Emiliania huxleyi CCMP 1516 to extremes of light is highly targeted. New Phytologist. 200 (1), 61-73

McKew, BA., Davey, P., Finch, SJ., Hopkins, J., Lefebvre, SC., Metodiev, MV., Oxborough, K., Raines, CA., Lawson, T. and Geider, RJ., (2013). The trade‐off between the light‐harvesting and photoprotective functions of fucoxanthin‐chlorophyll proteins dominates light acclimation in Emiliania huxleyi (clone CCMP 1516). New Phytologist. 200 (1), 74-85

DeFlorio, R., Brett, M-E., Waszczak, N., Apollinari, E., Metodiev, MV., Dubrovskyi, O., Eddington, D., Arkowitz, RA. and Stone, DE., (2013). Gβ phosphorylation is critical for efficient chemotropism in yeast. Journal of Cell Science. 126 (14), 2997-3009

Metodieva, G., Nogueira-de-Souza, NC., Greenwood, C., Al-Janabi, K., Leng, L., Bucala, R. and Metodiev, MV., (2013). CD74-dependent Deregulation of the Tumor Suppressor Scribble in Human Epithelial and Breast Cancer Cells. Neoplasia. 15 (6), 660-IN21

Parisis, N., Metodieva, G. and Metodiev, MV., (2013). Pseudopodial and β-arrestin-interacting proteomes from migrating breast cancer cells upon PAR2 activation. Journal of Proteomics. 80, 91-106

DeFlorio, R., Brett, M., Waszczak, N., Apollinari, E., Metodiev, M., Dubrovskyi, O., Eddington, D., Arkowitz, RA. and Stone, DE., (2013). Phosphorylation of G? is crucial for efficient chemotropism in yeast. Journal of Cell Science. 126 (14), 2997-3009

Karakikes, I., Morrison, IEG., O'Toole, P., Metodieva, G., Navarrete, CV., Gomez, J., Miranda‐Sayago, JM., Cherry, RJ., Metodiev, M. and Fernandez, N., (2012). Interaction of HLA‐DR and CD74 at the cell surface of antigen‐presenting cells by single particle image analysis. The FASEB Journal. 26 (12), 4886-4896

Greenwood, C., Metodieva, G., Al-Janabi, K., Lausen, B., Alldridge, L., Leng, L., Bucala, R., Fernandez, N. and Metodiev, MV., (2012). Stat1 and CD74 overexpression is co-dependent and linked to increased invasion and lymph node metastasis in triple-negative breast cancer. Journal of Proteomics. 75 (10), 3031-3040

Howard, TP., Fryer, MJ., Singh, P., Metodiev, M., Lytovchenko, A., Obata, T., Fernie, AR., Kruger, NJ., Quick, WP., Lloyd, JC. and Raines, CA., (2011). Antisense Suppression of the Small Chloroplast Protein CP12 in Tobacco Alters Carbon Partitioning and Severely Restricts Growth  . Plant Physiology. 157 (2), 620-631

Metodiev, MV., (2011). Applications of Nanoscale Liquid Chromatography Coupled to Tandem Mass Spectrometry in Quantitative Studies of Protein Expression, Protein–Protein Interaction, and Protein Phosphorylation. Methods in molecular biology (Clifton, N.J.). 790, 99-113

Metodieva, G., Greenwood, C., Alldridge, L., Sauven, P. and Metodiev, M., (2009). A peptide‐centric approach to breast cancer biomarker discovery utilizing label‐free multiple reaction monitoring mass spectrometry. PROTEOMICS – Clinical Applications. 3 (1), 78-82

Zaichick, SV., Metodiev, MV., Nelson, SA., Durbrovskyi, O., Draper, E., Cooper, JA. and Stone, DE., (2009). The Mating-specific Gα Interacts with a Kinesin-14 and Regulates Pheromone-induced Nuclear Migration in Budding Yeast. Molecular Biology of the Cell. 20 (12), 2820-2830

Howard, TP., Metodiev, M., Lloyd, JC. and Raines, CA., (2008). Thioredoxin-mediated reversible dissociation of a stromal multiprotein complex in response to changes in light availability. Proceedings of the National Academy of Sciences. 105 (10), 4056-4061

Krey, G., Frank, P., Shaikly, V., Barrientos, G., Cordo-Russo, R., Ringel, F., Moschansky, P., Chernukhin, IV., Metodiev, M., Fernández, N., Klapp, BF., Arck, PC. and Blois, SM., (2008). In vivo dendritic cell depletion reduces breeding efficiency, affecting implantation and early placental development in mice. Journal of Molecular Medicine. 86 (9), 999-1011

Alldridge, L., Metodieva, G., Greenwood, C., Al-Janabi, K., Thwaites, L., Sauven, P. and Metodiev, M., (2008). Proteome Profiling of Breast Tumors by Gel Electrophoresis and Nanoscale Electrospray Ionization Mass Spectrometry. Journal of Proteome Research. 7 (4), 1458-1469

Metodiev, M. and Alldridge, L., (2008). Phosphoproteomics: A possible route to novel biomarkers of breast cancer. PROTEOMICS – Clinical Applications. 2 (2), 181-194

D'Arcy, V., Abdullaev, ZK., Pore, N., Docquier, F., Torrano, V., Chernukhin, I., Smart, M., Farrar, D., Metodiev, M., Fernandez, N., Richard, C., Delgado, MD., Lobanenkov, V. and Klenova, E., (2006). The Potential of BORIS Detected in the Leukocytes of Breast Cancer Patients as an Early Marker of Tumorigenesis. Clinical Cancer Research. 12 (20), 5978-5986

Matheos, D., Metodiev, M., Muller, E., Stone, D. and Rose, MD., (2004). Pheromone-induced polarization is dependent on the Fus3p MAPK acting through the formin Bni1p. The Journal of Cell Biology. 165 (1), 99-109

Metodiev, MV., Matheos, D., Rose, MD. and Stone, DE., (2002). Regulation of MAPK Function by Direct Interaction with the Mating-Specific Gα in Yeast. Science. 296 (5572), 1483-1486

Metodiev, MV., Kicheva, MI., Stoinova, ZG. and Popova, LP., (2002). Two-Dimensional Electrophoretic Analysis of Salicylic Acid-Induced Changes in Polypeptide Pattern of Barley Leaves. Biologia plantarum. 45 (4), 585-588

Cismowski, MJ., Metodiev, M., Draper, E. and Stone, DE., (2001). Biochemical Analysis of Yeast Gα Mutants That Enhance Adaptation to Pheromone. Biochemical and Biophysical Research Communications. 284 (2), 247-254

Metodiev, MV., (1998). Hornet venom induces abundant expression of specific polypeptides in young barley leaves. Journal of Experimental Botany. 49 (318), 27-32

Metodiev, MV., Tsonev, TD. and Popova, LP., (1996). Effect of jasmonic acid on the stomatal and nonstomatal limitation of leaf photosynthesis in barley leaves. Journal of Plant Growth Regulation. 15 (2), 75-80

METODIEV, M. and DEMIREVSKA-KEPOVA, K., (1992). Rubisco Quantitation in Leaves of Different Barley Varieties by Enzyme-Linked Immunosorbent Assay. Journal of Experimental Botany. 43 (2), 155-158

Ismael, A., Waszczak, N., Metodiev, M., Tian, W., Cao, Y., Liang, J., Suchkov, D., Arkowitz, R. and Stone, D., (2012). Receptor phosphorylation and polarization are regulated by G beta interaction with Yck1.

Metodiev, MV., (2011). Biomarkers research in Europe: focus on personalized medicine

Metodiev, MV., Timanova, A. and Stone, DE., (2004). Differential phosphoproteome profiling by affinity capture and tandem matrix‐assisted laser desorption/ionization mass spectrometry