Dr Hannah Adams
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Email
hradam@essex.ac.uk -
Telephone
+44 (0) 1206 872533
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Location
3SW.5.08, Colchester Campus
Profile
Biography
2024 - Present : Senior Research Officer • Working with Dr Boyd McKew on engineering hydrocarbon biodegradation and biosurfactant pathways 2013 - 2024 : Laboratory Technician/Senior Laboratory Technician - University of Essex • Supporting multiple research groups across two laboratories within the Protein Structure and Mechanism of Disease Group at the University of Essex. • Use of specialist equipment including Gryphon crystallisation robot, Accuri flow cytometer, plate readers, UV-spectrometer, EPR spectrometer and AKTAs for protein purification. • Training of students and other lab members in use of specialist equipment in the laboratory. • Supervision of students carrying out research within the laboratory. • Maintenance of laboratory stocks including chemicals, consumables and bacterial cell lines. • Maintenance of equipment within the laboratory. • Health and Safety training within the laboratory and maintaining all records are kept up to date. 2015 - Present : Member of Professor Hough's research group, University of Essex. Researching Cytochrome c' structure and function Membership of Professional Societies : Biochemical Society (2017-present) Funding Awards: UKRI Technician Grant £12000 (2024)
Qualifications
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PhD University of Essex, (2024)
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MSc Molecular Medicine University of Essex, (2011)
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BSc Genetics University of Essex, (2010)
Appointments
University of Essex
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Senior Research Officer, School of Life Sciences, University of Essex (19/9/2024 - present)
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Senior Laboratory Technician, School of Life Sciences, University of Essex (1/6/2022 - 18/9/2024)
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Laboratory Technician, School of Life Sciences, University of Essex (1/8/2013 - 31/5/2022)
Publications
Journal articles (8)
Adams, HR., Fujii, S., Pfalzgraf, HE., Smyth, P., Andrew, CR. and Hough, MA., (2025). Cytochromes P460 and c′-β: exploiting a novel fold for multiple functions. JBIC Journal of Biological Inorganic Chemistry. 30 (2), 181-207
Pfalzgraf, HE., Rao, AG., Sen, K., Adams, HR., Edwards, M., Lu, Y., Yong, C., Jaho, S., Tosha, T., Sugimoto, H., Horrell, S., Beilsten-Edmands, J., Owen, RL., Andrew, CR., Worrall, JAR., Tews, I., Mulholland, AJ., Hough, MA. and Keal, TW., (2025). Double crossed? Structural and computational studies of an unusually crosslinked haem in Methylococcus capsulatus cytochrome P460. Chemical Science. 16 (35), 16266-16283
Fujii, S., Wilson, MT., Adams, HR., Mikolajek, H., Svistunenko, DA., Smyth, P., Andrew, CR., Sambongi, Y. and Hough, MA., (2024). Conformational rigidity of cytochrome c'-α from a thermophile is associated with slow NO binding. Biophysical Journal. 123 (16), 2594-2603
Adams, HR., Svistunenko, DA., Wilson, MT., Fujii, S., Strange, RW., Hardy, ZA., Vazquez, PA., Dabritz, T., Streblow, GJ., Andrew, CR. and Hough, MA., (2023). A heme pocket aromatic quadrupole modulates gas binding to cytochrome c'-β: Implications for NO sensors.. Journal of Biological Chemistry. 299 (6), 104742-104742
Yoshimi, T., Fujii, S., Oki, H., Igawa, T., Adams, HR., Ueda, K., Kawahara, K., Ohkubo, T., Hough, MA. and Sambongi, Y., (2022). Crystal structure of thermally stable homodimeric cytochrome c'-β from Thermus thermophilus.. Acta crystallographica. Section F, Structural biology communications. 78 (Pt 6), 217-225
Adams, HR., Krewson, C., Vardanega, JE., Fujii, S., Moreno-Chicano, T., Sambongi, Y., Svistunenko, D., Paps, J., Andrew, CR. and Hough, MA., (2019). One fold, two functions: cytochrome P460 and cytochrome c′-β from the methanotroph Methylococcus capsulatus (Bath). Chemical Science. 10 (10), 3031-3041
Adams, HR., Krewson, C., Vardanega, JE., Fujii, S., Moreno-Chicano, T., Sambongi, Y., Svistunenko, D., Paps, J., Andrew, CR. and Hough, MA., (2019). Correction: One fold, two functions: cytochrome P460 and cytochrome c′-β from the methanotroph Methylococcus capsulatus (Bath). Chemical Science. 10 (36), 8490-8490
Adams, HR., Krewson, C., Vardanega, JE., Fujii, S., Moreno-Chicano, T., Sambongi, Y., Svistunenko, D., Paps, J., Andrew, CR. and Hough, MA., (2019). Correction: One fold, two functions: cytochrome P460 and cytochrome c′-β from the methanotroph Methylococcus capsulatus (Bath). Chemical Science. 10 (10), 3143-3143
Thesis dissertation (1)
Adams, HR., (2024). Structural and spectroscopic characterisation of Cytochrome c’ and Cytochrome P460 from Methylococcus capsulatus (Bath)