2020 applicants
People

Professor Christopher Cooper

Emeritus Professor
School of Life Sciences
Emeritus Professor
School of Sport, Rehabilitation and Exercise Sciences
Professor Christopher Cooper

Teaching and supervision

Previous supervision

Christopher John Mcmanus
Christopher John Mcmanus
Thesis title: Compression Under Pressure: Physiological and Methodological Factors Influencing the Effect of Compression Garments on Running Economy.
Degree subject: Sport and Exercise Science
Degree type: Doctor of Philosophy
Awarded date: 28/9/2020
Benjamin Jones
Benjamin Jones
Thesis title: Development of Wearable Near-Infrared Spectroscopy Technology in Sport
Degree subject: Sport and Exercise Science
Degree type: Doctor of Philosophy
Awarded date: 29/6/2015
Rebecca Suzanne Silkstone
Rebecca Suzanne Silkstone
Thesis title: Reducing the Toxicity of Hemoglobin By Modification of Tyrosine Electron Transfer Pathways: The Search for a Novel, Non-Toxic Hemoglobin-Based Oxygen Carrier
Degree subject: Biochemistry
Degree type: Doctor of Philosophy
Awarded date: 5/7/2013
Annika Helen Broster
Annika Helen Broster
Thesis title: The Relationship of Oxygen Uptake to the Energy Demand of Sprint Performance
Degree subject: Sport and Exercise Science
Degree type: Master of Science (by Dissertation)
Awarded date: 3/7/2013
Lindsay Farish- Carradice
Lindsay Farish- Carradice
Thesis title: The Effect of Respiratory Alkalosis on Repeated Sprint Cycle Performance
Degree subject: Sport and Exercise Science
Degree type: Master of Science (by Dissertation)
Awarded date: 3/7/2013
Catherine Mary Hesford
Catherine Mary Hesford
Thesis title: The Use of Portable Near Infrared Spectroscopy in Elite Sport
Degree subject: Sport and Exercise Science
Degree type: Doctor of Philosophy
Awarded date: 19/12/2012

Publications

Journal articles (224)

Cooper, CE., Silkstone, GGA., Simons, M., Gretton, S., Rajagopal, BS., Allen-Baume, V., Syrett, N., Shaik, T., Popa, G., Sheng, X., Bird, M., Choi, J-W., Piano, R., Ronda, L., Bettati, S., Paredi, G., Mozzarelli, A. and Reeder, BJ., (2020). Engineering hemoglobin to enable homogenous PEGylation without modifying protein functionality. Biomaterials Science. 8 (14), 3896-3906

Cooper, CE., Silkstone, GGA., Simons, M., Rajagopal, B., Syrett, N., Shaik, T., Gretton, S., Welbourn, E., Bülow, L., Eriksson, NL., Ronda, L., Mozzarelli, A., Eke, A., Mathe, D. and Reeder, BJ., (2019). Engineering tyrosine residues into hemoglobin enhances heme reduction, decreases oxidative stress and increases vascular retention of a hemoglobin based blood substitute. Free Radical Biology and Medicine. 134, 106-118

Jones, B., Parry, D. and Cooper, CE., (2018). Underwater near infrared spectroscopy (uNIRS) can measure training adaptations in adolescent swimmers. PeerJ. 6 (4), e4393-e4393

Mcmanus, CJ., Cooper, CE. and Collison, J., (2018). Performance comparison of the MOXY and PortaMon near-infrared spectroscopy muscle oximeters at rest and during exercise. Journal of Biomedical Optics. 23 (1), 1-1

Simons, M., Gretton, S., Silkstone, GG., Rajagopal, BS., Allen-Baume, V., Syrett, N., Shaik, T., Eriksson, N., Ronda, L., Mozzarelli, A., Strader, MB., Alayash, AI., Reeder, BJ. and Cooper, CE., (2018). Comparison of the oxidative reactivity of recombinant fetal and adult human hemoglobin: implications for the design of hemoglobin-based oxygen carriers.. Bioscience Reports. 38 (4)

Alomari, EAM., Ronda, L., Bruno, S., Paredi, G., Marchetti, M., Bettati, S., Olivari, D., Fumagalli, F., Novelli, D., Ristagno, G., Latini, R., Cooper, CE., Reeder, BJ. and Mozzarelli, A., (2018). High- and low-affinity PEGylated hemoglobin-based oxygen carriers: differential oxidative stress in a Guinea pig transfusion model. Free Radical Biology and Medicine. 124, 299-310

Gheorghiev, MD., Hosseini, F., Moran, J. and Cooper, CE., (2018). Effects of pseudoephedrine on parameters affecting exercise performance: a meta-analysis. Sports Medicine - Open. 4 (44), 44-

Welbourn, EM., Wilson, MT., Yusof, A., Metodiev, MV. and Cooper, CE., (2017). The mechanism of formation, structure and physiological relevance of covalent hemoglobin attachment to the erythrocyte membrane. Free Radical Biology and Medicine. 103, 95-106

Silkstone, RS., Silkstone, G., Baath, JA., Rajagopal, B., Nicholls, P., Reeder, BJ., Ronda, L., Bulow, L. and Cooper, CE., (2016). The βLys66Tyr Variant of Human Hemoglobin as a Component of a Blood Substitute. Advances in Experimental Medicine and Biology. 876, 455-460

Hettinga, FJ., Konings, MJ. and Cooper, CE., (2016). Differences in Muscle Oxygenation, Perceived Fatigue and Recovery between Long-Track and Short-Track Speed Skating. Frontiers in Physiology. 7 (619), 619-

Jones, B. and Cooper, CE., (2016). Underwater Near-Infrared Spectroscopy: Muscle Oxygen Changes in the Upper and Lower Extremities in Club Level Swimmers and Triathletes. Advances in Experimental Medicine and Biology. 876, 35-40

Silkstone, GGA., Silkstone, RS., Wilson, MT., Simons, M., Bülow, L., Kallberg, K., Ratanasopa, K., Ronda, L., Mozzarelli, A., Reeder, BJ. and Cooper, CE., (2016). Engineering tyrosine electron transfer pathways decreases oxidative toxicity in hemoglobin: implications for blood substitute design. Biochemical Journal. 473 (19), 3371-3383

Rong, Z. and Cooper, CE., (2016). Hemoglobin Effects on Nitric Oxide Mediated Hypoxic Vasodilation. Advances in Experimental Medicine and Biology. 876, 121-127

Jones, B., Hamilton, DK. and Cooper, CE., (2015). Muscle Oxygen Changes following Sprint Interval Cycling Training in Elite Field Hockey Players. PLOS ONE. 10 (3), e0120338-e0120338

Silaghi-Dumitrescu, R., Scurtu, F., Mason, MG., Svistunenko, DA., Wilson, MT. and Cooper, CE., (2015). The reaction of oxyhemoglobin with nitric oxide: EPR evidence for an iron(III)-nitrate intermediate. Inorganica Chimica Acta. 436, 179-183

Caldwell, M., Moroz, T., Hapuarachchi, T., Bainbridge, A., Robertson, NJ., Cooper, CE. and Tachtsidis, I., (2015). Modelling Blood Flow and Metabolism in the Preclinical Neonatal Brain during and Following Hypoxic-Ischaemia. PLOS ONE. 10 (10), e0140171-e0140171

Cooper, C., (2015). Is artificial blood safe for vampires to eat?. Biochemist. 37 (6), 10-13

Deli, MA., Caldwell, M., Moroz, T., Hapuarachchi, T., Bainbridge, A., Robertson, NJ., Cooper, CE. and Tachtsidis, I., (2015). Modelling Blood Flow and Metabolism in the Preclinical Neonatal Brain during and Following Hypoxic-Ischaemia. PloS One. 10 (10), creators-Cooper=3AChristopher_E=3A=3A

Jones, B., Hamilton, DK. and Cooper, CE., (2015). Muscle oxygen changes following sprint interval cycling training in elite field hockey players. PLoS ONE. 10 (3), creators-Cooper=3AChristopher_E=3A=3A

Mason, MG., Nicholls, P. and Cooper, CE., (2014). Re-evaluation of the near infrared spectra of mitochondrial cytochrome c oxidase: Implications for non invasive in vivo monitoring of tissues. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1837 (11), 1882-1891

Jones, B. and Cooper, CE., (2014). Use of NIRS to Assess Effect of Training on Peripheral Muscle Oxygenation Changes in Elite Rugby Players Performing Repeated Supramaximal Cycling Tests. Advances in Experimental Medicine and Biology. 812, 333-339

Jones, B., Dat, M. and Cooper, CE., (2014). Underwater near-infrared spectroscopy measurements of muscle oxygenation: laboratory validation and preliminary observations in swimmers and triathletes. Journal of Biomedical Optics. 19 (12), 127002-127002

Silaghi-Dumitrescu, R., Svistunenko, DA., Cioloboc, D., Bischin, C., Scurtu, F. and Cooper, CE., (2014). Nitrite binding to globins: linkage isomerism, EPR silence and reductive chemistry. Nitric Oxide: Biology and Chemistry. 42, 32-39

Kolyva, C., Ghosh, A., Tachtsidis, I., Highton, D., Cooper, CE., Smith, M. and Elwell, CE., (2014). Cytochrome c oxidase response to changes in cerebral oxygen delivery in the adult brain shows higher brain-specificity than haemoglobin. NeuroImage. 85, 234-244

Cooper, CE., (2014). The chemiosmotic theory. Biochemist. 36 (4), 23-24

Nicholls, P., Marshall, DCA., Cooper, CE. and Wilson, MT., (2014). Sulfide complex formation and redox interactions with heme enzymes. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1837, creators-Wilson=3AMichael_T=3A=3A

Jones, B., Dat, M. and Cooper, CE., (2014). Underwater near-infrared spectroscopy measurements of muscle oxygenation: laboratory validation and preliminary observations in swimmers and triathletes. Journal of Biomedical Optics. 19 (12), creators-Cooper=3AChristopher_E=3A=3A

Cooper, CE., Schaer, DJ., Buehler, PW., Wilson, MT., Reeder, BJ., Silkstone, G., Svistunenko, DA., Bulow, L. and Alayash, AI., (2013). Haptoglobin Binding Stabilizes Hemoglobin Ferryl Iron and the Globin Radical on Tyrosine β145. Antioxidants & Redox Signaling. 18 (17), 2264-2273

Rong, Z. and Cooper, CE., (2013). Modeling Hemoglobin Nitrite Reductase Activity as a Mechanism of Hypoxic Vasodilation?. Advances in Experimental Medicine and Biology. 789, 361-368

Rong, Z., Banaji, M., Moroz, T. and Cooper, CE., (2013). Can Mitochondrial Cytochrome Oxidase Mediate Hypoxic Vasodilation Via Nitric Oxide Metabolism?. OXYGEN TRANSPORT TO TISSUE XXXIV. 765, 231-238

Rong, Z., Wilson, MT. and Cooper, CE., (2013). A model for the nitric oxide producing nitrite reductase activity of hemoglobin as a function of oxygen saturation. Nitric Oxide. 33, 74-80

Nicholls, P., Marshall, DC., Cooper, CE. and Wilson, MT., (2013). Sulfide inhibition of and metabolism by cytochrome c oxidase. Biochemical Society Transactions. 41 (5), 1312-1316

Jones, B., Hesford, CM. and Cooper, CE., (2013). The Use of Portable NIRS to Measure Muscle Oxygenation and Haemodynamics During a Repeated Sprint Running Test. Advances in Experimental Medicine and Biology. 789, 185-191

Hesford, C., Cardinale, M., Laing, S. and Cooper, CE., (2013). NIRS Measurements with Elite Speed Skaters: Comparison Between the Ice Rink and the Laboratory. OXYGEN TRANSPORT TO TISSUE XXXIV. 765, 81-86

Hesford, CM., Laing, S. and Cooper, CE., (2013). Using Portable NIRS to Compare Arm and Leg Muscle Oxygenation During Roller Skiing in Biathletes: A Case Study. Advances in Experimental Medicine and Biology. 789, 179-184

HESFORD, CM., LAING, S., CARDINALE, M. and COOPER, CE., (2013). Effect of Race Distance on Muscle Oxygenation in Short-Track Speed Skating. Medicine & Science in Sports & Exercise. 45 (1), 83-92

Rong, Z., Alayash, AI., Wilson, MT. and Cooper, CE., (2013). Modulating hemoglobin nitrite reductase activity through allostery: A mathematical model. Nitric Oxide. 35, 193-198

Kadiiska, MB., Basu, S., Brot, N., Cooper, C., Saari Csallany, A., Davies, MJ., George, MM., Murray, DM., Jackson Roberts, L., Shigenaga, MK., Sohal, RS., Stocker, R., Van Thiel, DH., Wiswedel, I., Hatch, GE. and Mason, RP., (2013). Biomarkers of oxidative stress study V: Ozone exposure of rats and its effect on lipids, proteins, and DNA in plasma and urine. Free Radical Biology and Medicine. 61, 408-415

Cooper, CE., Schaer, DJ., Buehler, PW., Wilson, MT., Reeder, BJ., Silkstone, G., Svistunenko, DA., Bulow, L. and Alayash, AI., (2013). Haptoglobin Binding Stabilizes Hemoglobin Ferryl Iron and the Globin Radical on Tyrosine β145. Antioxidants & Redox Signaling. 18 (17), 2264-2273

Silkstone, RS., Mason, MG., Nicholls, P. and Cooper, CE., (2012). Nitrogen dioxide oxidizes mitochondrial cytochrome c. Free Radical Biology and Medicine. 52 (1), 80-87

Coutts, LV., Cooper, CE., Elwell, CE. and Wilkins, AJ., (2012). Time course of the haemodynamic response to visual stimulation in migraine, measured using near-infrared spectroscopy. Cephalalgia. 32 (8), 621-629

Reeder, BJ., Svistunenko, DA., Cooper, CE. and Wilson, MT., (2012). Engineering Tyrosine-Based Electron Flow Pathways in Proteins: The Case of Aplysia Myoglobin. Journal of the American Chemical Society. 134 (18), 7741-7749

HESFORD, CM., LAING, SJ., CARDINALE, M. and COOPER, CE., (2012). Asymmetry of Quadriceps Muscle Oxygenation during Elite Short-Track Speed Skating. Medicine & Science in Sports & Exercise. 44 (3), 501-508

Wittekind, A., Cooper, CE., Elwell, CE., Leung, TS. and Beneke, R., (2012). Warm-up effects on muscle oxygenation, metabolism and sprint cycling performance. European Journal of Applied Physiology. 112 (8), 3129-3139

Jelfs, B., Banaji, M., Tachtsidis, I., Cooper, CE. and Elwell, CE., (2012). Modelling Noninvasively Measured Cerebral Signals during a Hypoxemia Challenge: Steps towards Individualised Modelling. PLoS ONE. 7 (6), e38297-e38297

Silaghi-Dumitrescu, R., Mich, M., Matyas, C. and Cooper, CE., (2012). Nitrite and nitrate reduction by molybdenum centers of the nitrate reductase type: Computational predictions on the catalytic mechanism. Nitric Oxide. 26 (1), 27-31

Kolyva, C., Tachtsidis, I., Ghosh, A., Moroz, T., Cooper, CE., Smith, M. and Elwell, CE., (2012). Systematic investigation of changes in oxidized cerebral cytochrome c oxidase concentration during frontal lobe activation in healthy adults. Biomedical Optics Express. 3 (10), 2550-2550

Moroz, T., Banaji, M., Robertson, NJ., Cooper, CE. and Tachtsidis, I., (2012). Computational modelling of the piglet brain to simulate near-infrared spectroscopy and magnetic resonance spectroscopy data collected during oxygen deprivation. Journal of The Royal Society Interface. 9 (72), 1499-1509

Cooper, C., (2012). Drug cheating at the Olympics: who, what, and why?. The Lancet. 380 (9836), 21-22

Cooper, C., (2012). Run, swim, throw, cheat: The future of drugs in sport. The Biochemist. 34 (3), 34-39

Coles, JA., Jelfs, B., Banaji, M., Tachtsidis, I., Cooper, CE. and Elwell, CE., (2012). Modelling Noninvasively Measured Cerebral Signals during a Hypoxemia Challenge: Steps towards Individualised Modelling. PloS One. 7 (6), creators-Cooper=3AChristopher_E=3A=3A

Marshall, DCA., Nicholls, P., Wilson, MT. and Cooper, CE., (2012). A comparison of nitric oxide and hydrogen sulphide interactions with mitochondrial cytochrome c oxidase. Nitric Oxide: Biology and Chemistry. 27, S11-S12

Rong, Z., Wilson, MT. and Cooper, CE., (2012). A model of the NO producing nitrite reductase activity of hemoglobin. Nitric Oxide: Biology and Chemistry. 27, creators-Wilson=3AMichael_T=3A=3A

Elwell, CE. and Cooper, CE., (2011). Making light work: illuminating the future of biomedical optics. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. 369 (1955), 4358-4379

Elwell, CE., Boas, DA., Cooper, CE., Delpy, D., Ferrari, M., Quaresima, V. and Yodh, AG., (2011). Britton Chance 1913–2010. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. 369 (1955), 4380-4389

Bischin, C., Deac, F., Silaghi-Dumitrescu, R., Worrall, JAR., Rajagopal, BS., Damian, G. and Cooper, CE., (2011). Ascorbate peroxidase activity of cytochromec. Free Radical Research. 45 (4), 439-444

Cooper, CE., Penfold, S-M., Elwell, CE. and Angus, C., (2010). Comparison of Local Adipose Tissue Content and SRS-Derived NIRS Muscle Oxygenation Measurements in 90 Individuals. Advances in Experimental Medicine and Biology. 662, 177-181

Banaji, M., Mallet, A., Elwell, CE., Nicholls, P., Tachtsidis, I., Smith, M. and Cooper, CE., (2010). Modelling of Mitochondrial Oxygen Consumption and NIRS Detection of Cytochrome Oxidase Redox State. Advances in Experimental Medicine and Biology. 662, 285-291

Binzoni, T., Cooper, CE., Wittekind, AL., Beneke, R., Elwell, CE., Van De Ville, D. and Leung, TS., (2010). A new method to measure local oxygen consumption in human skeletal muscle during dynamic exercise using near-infrared spectroscopy. Physiological Measurement. 31 (9), 1257-1269

Hesford, C., Cooper, CE. and Cardinale, M., (2010). Near Infrared Spectroscopy Measurements Of Muscle Metabolism In Elite Short-track Speed Skaters During On-ice Race Simulation. Medicine And Science In Sports And Exercise. 42 (5, 1), creators-Cooper=3AChristopher_E=3A=3A

Cooper, CE., Holladay, R., Nicholls, P., Svistunenko, DA., Mason, MG., Silkstone, G. and Wilson, MT., (2010). Nitric Oxide Interactions With Mitochondrial Cytochrome C And Cytochrome Oxidase. Free Radical Biology And Medicine. 49 (1), creators-Wilson=3AMichael_T=3A=3A

Cooper, CE., (2009). Radical Producing and Consuming Reactions of Hemoglobin: How Can We Limit Toxicity?. Artificial Organs. 33 (2), 110-114

Cooper, CE., Sharpe, MA., Mason, MG. and Nicholls, P., (2009). Steady State Redox Levels in Cytochrome Oxidase: Relevance for in Vivo Near Infrared Spectroscopy (Nirs). Advances in Experimental Medicine and Biology. 645, 123-128

Cooper, CE., Cope, M., Elwell, CE. and Delpy, DT., (2009). Bicuculline-Induced Seizures: A Challenge for Optical and Biochemical Modeling of the Cytochrome Oxidase CuA Nirs Signal. Advances in Experimental Medicine and Biology. 645, 129-134

Mason, MG., Nicholls, P. and Cooper, CE., (2009). The steady-state mechanism of cytochrome c oxidase: redox interactions between metal centres. Biochemical Journal. 422 (2), 237-246

Mason, MG., Shepherd, M., Nicholls, P., Dobbin, PS., Dodsworth, KS., Poole, RK. and Cooper, CE., (2009). Cytochrome bd confers nitric oxide resistance to Escherichia coli. Nature Chemical Biology. 5 (2), 94-96

Gaucher-Di Stasio, C., Paternotte, E., Prin-Mathieu, C., Reeder, BJ., Poitevin, G., Labrude, P., Stoltz, J-F., Cooper, CE. and Menu, P., (2009). The importance of the effect of shear stress on endothelial cells in determining the performance of hemoglobin based oxygen carriers. Biomaterials. 30 (4), 445-451

Reeder, BJ., Svistunenko, DA., Cooper, CE. and Wilson, MT., (2009). Engineering Electron Transfer Pathways in Myoglobin and Hemoglobin: A Route to Detoxify Blood Substitutes?. Free Radical Biology And Medicine. 47, creators-Wilson=3AMichael_T=3A=3A

Cooper, CE. and Brown, GC., (2008). The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance. Journal of Bioenergetics and Biomembranes. 40 (5), 533-539

Cooper, CE., Mason, MG. and Nicholls, P., (2008). A dynamic model of nitric oxide inhibition of mitochondrial cytochrome c oxidase. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1777 (7-8), 867-876

Cooper, CE., Silaghi-Dumitrescu, R., Rukengwa, M., Alayash, AI. and Buehler, PW., (2008). Peroxidase activity of hemoglobin towards ascorbate and urate: A synergistic protective strategy against toxicity of Hemoglobin-Based Oxygen Carriers (HBOC). Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1784 (10), 1415-1420

Cooper, CE., (2008). Drugs and ergogenic aids to improve sport performance. Essays in Biochemistry. 44, 1-10

Cooper, CE., (2008). The biochemistry of drugs and doping methods used to enhance aerobic sport performance. Essays in Biochemistry. 44, 63-84

Mason, MG., Holladay, RS., Nicholls, P., Shepherd, M. and Cooper, CE., (2008). A Quantitative Approach to Nitric Oxide Inhibition of Terminal Oxidases of the Respiratory Chain. GLOBINS AND OTHER NITRIC OXIDE-REACTIVE PROTEINS, PART B. 437, 135-159

Banaji, M., Mallet, A., Elwell, CE., Nicholls, P. and Cooper, CE., (2008). A Model of Brain Circulation and Metabolism: NIRS Signal Changes during Physiological Challenges. PLoS Computational Biology. 4 (11), e1000212-e1000212

Reeder, BJ., Grey, M., Silaghi-Dumitrescu, R-L., Svistunenko, DA., Bülow, L., Cooper, CE. and Wilson, MT., (2008). Tyrosine Residues as Redox Cofactors in Human Hemoglobin. Journal of Biological Chemistry. 283 (45), 30780-30787

Cooper, C. and Beneke, R., (2008). Essays in Biochemistry: Preface. Essays in Biochemistry. 44

Cooper, C., Silkstone, G., Mason, M., Nicholls, P. and Wilson, M., (2008). S10/1 Interactions of nitric oxide with cytochrome c and cytochrome c oxidase. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1777, S57-S58

Nicholls, P. and Cooper, CE., (2008). Does cytochrome c oxidase pump protons in the controlled state?. Biochimica Et Biophysica Acta-Bioenergetics. 1777 (S), creators-Cooper=3AChristopher_E=3A=3A

Nicholls, P. and Cooper, CE., (2008). Does cytochrome c oxidase pump protons in the controlled state?. Biochimica et Biophysica Acta - Bioenergetics. 1777 (S), creators-Cooper=3AChristopher_E=3A=3A

Cooper, CE., (2008). Drugs and ergogenic aids to improve sport performance.. Essays in biochemistry. 44, 1-10

Cooper, CE., Silkstone, G., Mason, MG., Nicholls, P. and Wilson, MT., (2008). Interactions of nitric oxide with cytochrome c and cytochrome c oxidase. Biochimica et Biophysica Acta: Bioenergetics. 1777, S57-S58

Mason, MG., Nicholls, P. and Cooper, CE., (2008). Steady state redox interactions of cytochrome c oxidase. Biochimica et Biophysica Acta - Bioenergetics. 1777 (S), creators-Cooper=3AChristopher_E=3A=3A

Banaji, M., Mallet, A., Elwell, CE., Nicholls, P. and Cooper, CE., (2008). A model of brain circulation and metabolism: NIRS signal changes during physiological challenges.. PLoS computational biology. 4 (11), creators-Cooper=3AChristopher_E=3A=3A

Cooper, CE. and Giulivi, C., (2007). Nitric oxide regulation of mitochondrial oxygen consumption II: molecular mechanism and tissue physiology. American Journal of Physiology-Cell Physiology. 292 (6), C1993-C2003

Svistunenko, DA., Reeder, BJ., Wankasi, MM., Silaghi-Dumitrescu, R-L., Cooper, CE., Rinaldo, S., Cutruzzol?, F. and Wilson, MT., (2007). Reaction of Aplysia limacina metmyoglobin with hydrogen peroxide. Dalton Transactions (8), 840-840

Silaghi-Dumitrescu, R., Reeder, BJ., Nicholls, P., Cooper, CE. and Wilson, MT., (2007). Ferryl haem protonation gates peroxidatic reactivity in globins. Biochemical Journal. 403 (3), 391-395

Pipirou, Z., Bottrill, AR., Svistunenko, DA., Efimov, I., Basran, J., Mistry, SC., Cooper, CE. and Raven, EL., (2007). The Reactivity of Heme in Biological Systems:  Autocatalytic Formation of Both Tyrosine−Heme and Tryptophan−Heme Covalent Links in a Single Protein Architecture†. Biochemistry. 46 (46), 13269-13278

Tachtsidis, I., Tisdall, M., Leung, TS., Cooper, CE., Delpy, DT., Smith, M. and Elwell, CE., (2007). Investigation ofin vivomeasurement of cerebral cytochrome-c-oxidase redox changes using near-infrared spectroscopy in patients with orthostatic hypotension. Physiological Measurement. 28 (2), 199-211

Griffin, M., Prior, D., Cooper, CE., Wilkins, AJ. and Elwell, CE., (2006). Near Infrared Spectroscopy as a Non-Invasive Assessment of Cortical Abnormality in Migraine?. Advances in Experimental Medicine and Biology. 578, 203-208

Cooper, CE., Pryor, D., Hall, C. and Griffin, M., (2006). NIRS-Detected Changes in the Motor Cortex During Mental Rehearsal of Physical Activity (Imaginary Exercise). Advances in Experimental Medicine and Biology. 578, 185-190

Cooper, CE., Blannin, M., Hall, C. and Griffin, M., (2006). NIRS-Detected Changes in the Arm During Mental Rehearsal of Physical Activity (Imaginary Exercise). Advances in Experimental Medicine and Biology. 578, 191-196

Mason, MG., Nicholls, P., Wilson, MT. and Cooper, CE., (2006). Nitric oxide inhibition of respiration involves both competitive (heme) and noncompetitive (copper) binding to cytochrome c oxidase. Proceedings of the National Academy of Sciences. 103 (3), 708-713

Dunne, J., Caron, A., Menu, P., Alayash, AI., Buehler, PW., Wilson, MT., Silaghi-Dumitrescu, R., Faivre, B. and Cooper, CE., (2006). Ascorbate removes key precursors to oxidative damage by cell-free haemoglobin in vitro and in vivo. Biochemical Journal. 399 (3), 513-524

Svistunenko, DA., Davies, N., Brealey, D., Singer, M. and Cooper, CE., (2006). Mitochondrial dysfunction in patients with severe sepsis: An EPR interrogation of individual respiratory chain components. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1757 (4), 262-272

Giulivi, C., Kato, K. and Cooper, CE., (2006). Nitric oxide regulation of mitochondrial oxygen consumption I: cellular physiology. American Journal of Physiology-Cell Physiology. 291 (6), C1225-C1231

VOLLAARD, NBJ., COOPER, CE. and SHEARMAN, JP., (2006). Exercise-Induced Oxidative Stress in Overload Training and Tapering. Medicine & Science in Sports & Exercise. 38 (7), 1335-1341

Griffin, M., Prior, D., Cooper, CE., Wilkins, AJ. and Elwell, CE., (2006). Near infrared spectroscopy as a noninvasive assessment of cortical abnormality in migraine?. Advances in experimental medicine and biology. 578, 203-208

Cooper, CE., Blannin, M., Hall, C. and Griffin, M., (2006). NIRS-detected changes in the arm during mental rehearsal of physical activity (imaginary exercise).. Advances in experimental medicine and biology. 578, 191-196

Cooper, CE., Pryor, D., Hall, C. and Griffin, M., (2006). NIRS-detected changes in the motor cortex during mental rehearsal of physical activity (imaginary exercise).. Advances in experimental medicine and biology. 578, 185-190

Myers, DE., Cooper, CE., Beilman, GJ., Mowlem, JD., Anderson, LAD., Seifert, RP. and Ortner, JP., (2006). A wide gap second derivative NIR spectroscopic method for measuring tissue hemoglobin oxygen saturation.. Advances in experimental medicine and biology. 578, 217-222

Cooper, C., Crowther, T., Smith, BM., Isaac, S. and Collin, HA., (2006). Assessment of the response of carrot somaclones to Pythium violae, causal agent of cavity spot. Plant Pathology. 55 (3), 427-432

Cooper, CE., Jurd, M., Nicholls, P., Wankasi, MM., Svistunenko, DA., Reeder, BJ. and Wilson, MT., (2005). On the formation, nature, stability and biological relevance of the primary reaction intermediates of myoglobins with hydrogen peroxide. Dalton Transactions (21), 3483-3483

Silaghi-Dumitrescu, R. and Cooper, CE., (2005). Transient species involved in catalytic dioxygen/peroxide activation by hemoproteins: possible involvement of protonated Compound I species. Dalton Transactions (21), 3477-3477

Silkstone, GG., Cooper, CE., Svistunenko, D. and Wilson, MT., (2005). EPR and Optical Spectroscopic Studies of Met80X Mutants of Yeast Ferricytochromec. Models for Intermediates in the Alkaline Transition. Journal of the American Chemical Society. 127 (1), 92-99

Vollaard, NBJ., Reeder, BJ., Shearman, JP., Menu, P., Wilson, MT. and Cooper, CE., (2005). A new sensitive assay reveals that hemoglobin is oxidatively modified in vivo. Free Radical Biology and Medicine. 39 (9), 1216-1228

Davies, NA., Brealey, DA., Stidwill, R., Singer, M., Svistunenko, DA. and Cooper, CE., (2005). Nitrosyl heme production compared in endotoxemic and hemorrhagic shock. Free Radical Biology and Medicine. 38 (1), 41-49

Vollaard, NBJ., Shearman, JP. and Cooper, CE., (2005). Exercise-Induced Oxidative Stress. Sports Medicine. 35 (12), 1045-1062

Myers, DE., Anderson, LD., Seifert, RP., Ortner, JP., Cooper, CE., Beilman, GJ. and Mowlem, JD., (2005). Noninvasive method for measuring local hemoglobin oxygen saturation in tissue using wide gap second derivative near-infrared spectroscopy. Journal of Biomedical Optics. 10 (3), 034017-034017

Cooper, C., (2004). Competitive, Reversible, Physiological? Inhibition of Mitochondrial Cytochrome Oxidase by Nitric Oxide. IUBMB Life. 55 (10), 591-597

Svistunenko, DA. and Cooper, CE., (2004). A New Method of Identifying the Site of Tyrosyl Radicals in Proteins. Biophysical Journal. 87 (1), 582-595

Reeder, BJ., Svistunenko, DA., Cooper, CE. and Wilson, MT., (2004). The Radical and Redox Chemistry of Myoglobin and Hemoglobin: From In Vitro Studies to Human Pathology. Antioxidants and Redox Signaling. 6 (6), 954-966

Svistunenko, DA., Wilson, MT. and Cooper, CE., (2004). Tryptophan or tyrosine? On the nature of the amino acid radical formed following hydrogen peroxide treatment of cytochrome c oxidase. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1655 (1-3), 372-380

Vanin, AF., Svistunenko, DA., Mikoyan, VD., Serezhenkov, VA., Fryer, MJ., Baker, NR. and Cooper, CE., (2004). Endogenous Superoxide Production and the Nitrite/Nitrate Ratio Control the Concentration of Bioavailable Free Nitric Oxide in Leaves. Journal of Biological Chemistry. 279 (23), 24100-24107

Malone, SA., Lewin, A., Kilic, MA., Svistunenko, DA., Cooper, CE., Wilson, MT., Le Brun, NE., Spiro, S. and Moore, GR., (2004). Protein-Template-Driven Formation of Polynuclear Iron Species†. Journal of the American Chemical Society. 126 (2), 496-504

BORRELLY, GPM., BLINDAUER, CA., SCHMID, R., BUTLER, CS., COOPER, CE., HARVEY, I., SADLER, PJ. and ROBINSON, NJ., (2004). A novel copper site in a cyanobacterial metallochaperone. Biochemical Journal. 378 (2), 293-297

Reeder, BJ., Svistunenko, DA., Cooper, CE. and Wilson, MT., (2004). The Radical and Redox Chemistry of Myoglobin and Hemoglobin: From In Vitro Studies to Human Pathology. Antioxidants & Redox Signaling. 6 (6), 954-966

(2004). Correction. Biophysical Journal. 87 (5), 3614-3616

Cooper, C., Isaac, S., Jones, MG., Crowther, T., Smith, BM. and Collin, HA., (2004). Morphological and biochemical response of carrots to Pythium violae, causative agent of Cavity Spot. Physiological and Molecular Plant Pathology. 64 (1), 27-35

Cooper, CE., Davies, NA., Psychoulis, M., Canevari, L., Bates, TE., Dobbie, MS., Casley, CS. and Sharpe, MA., (2003). Nitric oxide and peroxynitrite cause irreversible increases in the Km for oxygen of mitochondrial cytochrome oxidase: in vitro and in vivo studies. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1607 (1), 27-34

Cooper, CE. and Angus, C., (2003). Blood Volume Changes are Controlled Centrally Not Locally - A Near-Infrared Spectroscopy Study of One Legged Aerobic Exercise. Advances in Experimental Medicine and Biology. 530, 627-635

Svistunenko, DA., Reeder, BJ., Wilson, MT. and Cooper, CE., (2003). Radical Formation and Migration in Myoglobins. Progress in Reaction Kinetics and Mechanism. 28 (1), 105-118

Davies, NA., Cooper, CE., Stidwill, R. and Singer, M., (2003). Inhibition of Mitochondrial Respiration During Early Stage Sepsis. Advances in Experimental Medicine and Biology. 530, 725-736

McHugh, JP., Rodríguez-Quiñones, F., Abdul-Tehrani, H., Svistunenko, DA., Poole, RK., Cooper, CE. and Andrews, SC., (2003). Global Iron-dependent Gene Regulation inEscherichia coli. Journal of Biological Chemistry. 278 (32), 29478-29486

Murphy, MP., Echtay, KS., Blaikie, FH., Asin-Cayuela, J., Cochemé, HM., Green, K., Buckingham, JA., Taylor, ER., Hurrell, F., Hughes, G., Miwa, S., Cooper, CE., Svistunenko, DA., Smith, RAJ. and Brand, MD., (2003). Superoxide Activates Uncoupling Proteins by Generating Carbon-centered Radicals and Initiating Lipid Peroxidation. Journal of Biological Chemistry. 278 (49), 48534-48545

Sen, S., Ratnaraj, N., Davies, NA., Mookerjee, RP., Cooper, CE., Patsalos, PN., Williams, R. and Jalan, R., (2003). Treatment of Phenytoin Toxicity by the Molecular Adsorbents Recirculating System (MARS). Epilepsia. 44 (2), 265-267

Cooper, CE., (2002). Nitric oxide and cytochrome oxidase: substrate, inhibitor or effector?. Trends in Biochemical Sciences. 27 (1), 33-39

Cooper, CE., Vollaard, NBJ., Choueiri, T. and Wilson, MT., (2002). Exercise, free radicals and oxidative stress. Biochemical Society Transactions. 30 (2), 280-285

Torres, J., Svistunenko, D., Karlsson, B., Cooper, CE. and Wilson, MT., (2002). Fast Reduction of a Copper Center in Laccase by Nitric Oxide and Formation of a Peroxide Intermediate. Journal of the American Chemical Society. 124 (6), 963-967

Cooper, CE., Patel, RP., Brookes, PS. and Darley-Usmar, VM., (2002). Nanotransducers in cellular redox signaling: modification of thiols by reactive oxygen and nitrogen species. Trends in Biochemical Sciences. 27 (10), 489-492

Svistunenko, DA., Dunne, J., Fryer, M., Nicholls, P., Reeder, BJ., Wilson, MT., Bigotti, MG., Cutruzzolà, F. and Cooper, CE., (2002). Comparative Study of Tyrosine Radicals in Hemoglobin and Myoglobins Treated with Hydrogen Peroxide. Biophysical Journal. 83 (5), 2845-2855

VOEVODSKAYA, NV., SEREZHENKOV, VA., COOPER, CE., KUBRINA, LN. and VANIN, AF., (2002). Exogenous ferrous iron is required for the nitric oxide-catalysed destruction of the iron–sulphur centre in adrenodoxin. Biochemical Journal. 368 (2), 633-639

Brealey, D., Brand, M., Hargreaves, I., Heales, S., Land, J., Smolenski, R., Davies, NA., Cooper, CE. and Singer, M., (2002). Association between mitochondrial dysfunction and severity and outcome of septic shock. The Lancet. 360 (9328), 219-223

Kayyali, R., Porter, JB., Liu, ZD., Davies, NA., Nugent, JH., Cooper, CE. and Hider, RC., (2001). Structure-Function Investigation of the Interaction of 1- and 2-Substituted 3-Hydroxypyridin-4-ones with 5-Lipoxygenase and Ribonucleotide Reductase. Journal of Biological Chemistry. 276 (52), 48814-48822

ALDERTON, WK., COOPER, CE. and KNOWLES, RG., (2001). Nitric oxide synthases: structure, function and inhibition. Biochemical Journal. 357 (3), 593-593

Cooper, CE. and Davies, NA., (2000). Effects of nitric oxide and peroxynitrite on the cytochrome oxidase Km for oxygen: implications for mitochondrial pathology. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1459 (2-3), 390-396

Torres, J., Sharpe, MA., Rosquist, A., Cooper, CE. and Wilson, MT., (2000). Cytochrome c oxidase rapidly metabolises nitric oxide to nitrite. FEBS Letters. 475 (3), 263-266

Cooper, CE. and Wyatt, JS., (2000). NMR spectroscopy and imaging of the neonatal brain. Biochemical Society Transactions. 28 (2), 121-126

Svistunenko, DA., Sharpe, MA., Nicholls, P., Wilson, MT. and Cooper, CE., (2000). A New Method for Quantitation of Spin Concentration by EPR Spectroscopy: Application to Methemoglobin and Metmyoglobin. Journal of Magnetic Resonance. 142 (2), 266-275

SVISTUNENKO, DA., SHARPE, MA., NICHOLLS, P., BLENKINSOP, C., DAVIES, NA., DUNNE, J., WILSON, MT. and COOPER, CE., (2000). The pH dependence of naturally occurring low-spin forms of methaemoglobin and metmyoglobin: an EPR study. Biochemical Journal. 351 (3), 595-605

SVISTUNENKO, DA., SHARPE, MA., NICHOLLS, P., BLENKINSOP, C., DAVIES, NA., DUNNE, J., WILSON, MT. and COOPER, CE., (2000). The pH dependence of naturally occurring low-spin forms of methaemoglobin and metmyoglobin: an EPR study. Biochemical Journal. 351 (3), 595-595

Cooper, CE., (1999). Nitric oxide and iron proteins. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1411 (2-3), 290-309

Angus, C., Welford, D., Sellens, M., Thompson, S. and Cooper, CE., (1999). Estimation of Lactate Threshold by Near Infrared Spectroscopy. Advances in Experimental Medicine and Biology. 471, 283-288

Svistunenko, DA., Rob, A., Ball, A., Torres, J., Symons, MCR., Wilson, MT. and Cooper, CE., (1999). The electron paramagnetic resonance characterisation of a copper-containing extracellular peroxidase from Thermomonospora fusca BD25. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1434 (1), 74-85

Cooper, CE., (1999). Biochemistry of nitric oxide. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1411 (2-3), 215-216

Cooper, CE., (1999). In vivo measurements of mitochondrial function and cell death following hypoxic/ischaemic damage to the new-born brain. Biochemical Society Symposia. 66, 123-140

Cooper, CE., Cope, M., Springett, R., Amess, PN., Penrice, J., Tyszczuk, L., Punwani, S., Ordidge, R., Wyatt, J. and Delpy, DT., (1999). Use of Mitochondrial Inhibitors to Demonstrate That Cytochrome Oxidase Near-Infrared Spectroscopy Can Measure Mitochondrial Dysfunction Noninvasively in the Brain. Journal of Cerebral Blood Flow & Metabolism. 19 (1), 27-38

Heekeren, HR., Kohl, M., Obrig, H., Wenzel, R., von Pannwitz, W., Matcher, SJ., Dirnagl, U., Cooper, CE. and Villringer, A., (1999). Noninvasive Assessment of Changes in Cytochrome-c Oxidase Oxidation in Human Subjects during Visual Stimulation. Journal of Cerebral Blood Flow & Metabolism. 19 (6), 592-603

COOPER, CE., DELPY, DT. and NEMOTO, EM., (1998). The relationship of oxygen delivery to absolute haemoglobin oxygenation and mitochondrial cytochrome oxidase redox state in the adult brain: a near-infrared spectroscopy study. Biochemical Journal. 332 (3), 627-632

Dunne, J., Svistunenko, DA., Wilson, MT., Alayash, AI. and Cooper, CE., (1998). Reactions of cross-linked ferric haemoglobins with hydrogen peroxide. Biochemical Society Transactions. 26 (4), 9-15

Torres, J., Cooper, CE., Sharpe, M. and Wilson, MT., (1998). Reactivity of nitric oxide with cytochrome c oxidase: Interactions with the binuclear centre and mechanism of inhibition. Journal of Bioenergetics and Biomembranes. 30 (1), 63-69

Sharpe, MA. and Cooper, CE., (1998). Interaction of Peroxynitrite with Mitochondrial Cytochrome Oxidase. Journal of Biological Chemistry. 273 (47), 30961-30972

SHARPE, MA. and COOPER, CE., (1998). Reactions of nitric oxide with mitochondrial cytochrome c: a novel mechanism for the formation of nitroxyl anion and peroxynitrite. Biochemical Journal. 332 (1), 9-19

Cooper, CE., Torres, J., Sharpe, MA., Wilson, MT. and Svistunenko, DA., (1998). Peroxynitrite Reacts with Methemoglobin to Generate Globin-Bound Free Radical Species. Advances in Experimental Medicine and Biology. 454, 195-202

Torres, J., Cooper, CE. and Wilson, MT., (1998). A Common Mechanism for the Interaction of Nitric Oxide with the Oxidized Binuclear Centre and Oxygen Intermediates of CytochromecOxidase. Journal of Biological Chemistry. 273 (15), 8756-8766

Firbank, M., Elwell, CE., Cooper, CE. and Delpy, DT., (1998). Experimental and theoretical comparison of NIR spectroscopy measurements of cerebral hemoglobin changes. Journal of Applied Physiology. 85 (5), 1915-1921

Quaresima, V., Springett, R., Cope, M., Wyatt, JT., Delpy, DT., Ferrari, M. and E. Cooper, C., (1998). Oxidation and reduction of cytochrome oxidase in the neonatal brain observed by in vivo near-infrared spectroscopy. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1366 (3), 291-300

Moore, KP., Holt, SG., Patel, RP., Svistunenko, DA., Zackert, W., Goodier, D., Reeder, BJ., Clozel, M., Anand, R., Cooper, CE., Morrow, JD., Wilson, MT., Darley-Usmar, V. and Roberts, LJ., (1998). A Causative Role for Redox Cycling of Myoglobin and Its Inhibition by Alkalinization in the Pathogenesis and Treatment of Rhabdomyolysis-induced Renal Failure. Journal of Biological Chemistry. 273 (48), 31731-31737

Nicholls, P., Sharpe, M., Torres, J., Wilson, MT. and Cooper, CE., (1998). 24 Nitric oxide as an effector and a substrate for cytochrome c oxidase. Biochemical Society Transactions. 26 (4), S323-S323

Dunne, J., Svistunenko, DA., Wilson, MT., Alayash, AI. and Cooper, CE., (1998). 20 Reactions of cross-linked ferric haemoglobins with hydrogen peroxide. Biochemical Society Transactions. 26 (4), S320-S320

Punwani, S., Ordidge, RJ., Cooper, CE., Amess, P. and Clemence, M., (1998). MRI measurements of cerebral deoxyhaemoglobin concentration [dHb]—correlation with near infrared spectroscopy (NIRS). NMR in Biomedicine. 11 (6), 281-289

Roberts, IG., Fallon, P., Kirkham, FJ., Kirshbom, PM., Cooper, CE., Elliott, MJ. and Edwards, AD., (1998). Measurement of cerebral blood flow during cardiopulmonary bypass with near-infrared spectroscopy. The Journal of Thoracic and Cardiovascular Surgery. 115 (1), 94-102

(1997). Nitric oxide ejects electrons from the binuclear centre of cytochromecoxidase by reacting with oxidised copper: a general mechanism for the interaction of copper proteins with nitric oxide?. FEBS Letters. 414 (2), 281-284

Wilson, MT., Torres, J., Cooper, CE. and Sharpe, MA., (1997). Interactions of cytochrome c oxidase with nitric oxide: reactions of the ‘turnover’ intermediates. Biochemical Society Transactions. 25 (3), 905-909

Cooper, CE. and Porter, JB., (1997). Ribonucleotide reductase, lipoxygenase and the intracellular low-molecular-weight iron pool. Biochemical Society Transactions. 25 (1), 75-80

Cooper, CE. and Springett, R., (1997). Measurement of cytochrome oxidase and mitochondrial energetics by near–infrared spectroscopy. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 352 (1354), 669-676

Cooper, CE., Cope, M., Quaresima, V., Ferrari, M., Nemoto, E., Springett, R., Matcher, S., Amess, P., Penrice, J., Tyszczuk, L., Wyatt, J. and Delpy, DT., (1997). Measurement of Cytochrome Oxidase Redox State by Near Infrared Spectroscopy. Advances in Experimental Medicine and Biology. 413, 63-73

DAVIES, NA., TRIKKAS, C. and COOPER, CE., (1997). Does carbon monoxide inhibit cytochrome oxidase in vivo?. Biochemical Society Transactions. 25 (3), 406S-406S

SHARPE, MA. and COOPER, CE., (1997). Nitric Oxide Reacts With Mitochondrial Cytochrome c. Biochemical Society Transactions. 25 (3), 407S-407S

SPRINGETT, RJ., PENRICE, JM., AMESS, PN., TYSZCZUK, L., DELPY, DT., WYATT, JS. and COOPER, CE., (1997). Non-Invasive measurements of mitochondrial damage during neonatal hypoxia-Ischaemia - a role for nitric oxide?. Biochemical Society Transactions. 25 (3), 398S-398S

Villringer, A., Heekeren, HR., Obrig, H., V. Pannwitz, W., Ramshorn, A., Kohl, M., Villringer, K. and Cooper, C., (1997). Cytochrome-oxidase oxidation in the occipital cortex during visual stimulation - A whole-spectrum near-infrared spectroscopy study. NeuroImage. 5 (4 PART II)

Wilson, MT., Torres, J., Sharpe, M. and Cooper, C., (1997). Reactions of Ntric Oxide with Cytochrome c Oxidase. Biochemical Society Transactions. 25 (3), 383S-383S

Penrice, J., Lorek, A., Cady, EB., Amess, PN., Wylezinska, M., Cooper, CE., D'Souza, P., Brown, GC., Kirkbride, V., Edwards, AD., Wyatt, JS. and Reynolds, EOR., (1997). Proton Magnetic Resonance Spectroscopy of the Brain during Acute Hypoxia-Ischemia and Delayed Cerebral Energy Failure in the Newborn Piglet. Pediatric Research. 41 (6), 795-802

Amess, PN., Penrice, J., Cady, EB., Lorek, A., Wylezinska, M., Cooper, CE., D'Souza, P., Tyszczuk, L., Thoresen, M., Edwards, AD., Wyatt, JS. and Reynolds, EOR., (1997). Mild Hypothermia after Severe Transient Hypoxia-Ischemia Reduces the Delayed Rise in Cerebral Lactate in the Newborn Piglet. Pediatric Research. 41 (6), 803-808

Punwani, S., Cooper, CE., Clemence, M., Penrice, J., Amess, P., Thornton, J. and Ordidge, RJ., (1997). Correlation between Absolute Deoxyhaemoglobin [dHb] Measured by Near Infrared Spectroscopy (NIRS) and Absolute R2′ as Determined by Magnetic Resonance Imaging (MRI). Advances in Experimental Medicine and Biology. 413, 129-137

Yue, X., Mehmet, H., Penrice, J., Cooper, C., Cady, E., Wyatt, JS., Reynolds, EOR., Edwards, AD. and Squier, MV., (1997). Apoptosis and necrosis in the newborn piglet brain following transient cerebral hypoxia-ischaemia. Neuropathology and Applied Neurobiology. 23 (1), 16-25

COOPER, CE., PEZESHK, A., TORRES, J., WILSON, M. and SYMONS, MRC., (1996). A new EPR signal from cytochrome oxidase - evidence for conformational flexibility at the CuB site?. Biochemical Society Transactions. 24 (3), 465S-465S

COOPER, CE., PANAGIOTOPOULUOROGER, JSA. and PENRICE, J., (1996). Near infrared spectroscopy of nitrosyl haemoglobin - relevance to in vivo detection of nitric oxide. Biochemical Society Transactions. 24 (3), 448S-448S

Cooper, CE., Lynagh, GR., Hoyes, KP., Hider, RC., Cammack, R. and Porter, JB., (1996). The Relationship of Intracellular Iron Chelation to the Inhibition and Regeneration of Human Ribonucleotide Reductase. Journal of Biological Chemistry. 271 (34), 20291-20299

Cooper, CE., Elwell, CE., Meek, JH., Matcher, SJ., Wyatt, JS., Cope, M. and Delpy, DT., (1996). The Noninvasive Measurement of Absolute Cerebral Deoxyhemoglobin Concentration and Mean Optical Path Length in the Neonatal Brain by Second Derivative Near Infrared Spectroscopy. Pediatric Research. 39 (1), 32-38

Abeysinghe, RD., Roberts, PJ., Cooper, CE., MacLean, KH., Hider, RC. and Porter, JB., (1996). The Environment of the Lipoxygenase Iron Binding Site Explored with Novel Hydroxypyridinone Iron Chelators. Journal of Biological Chemistry. 271 (14), 7965-7972

Shergill, JK., Cammack, R., Cooper, CE., Cooper, JM., Mann, VM. and Schapira, AHV., (1996). Detection of Nitrosyl Complexes in Human Substantia Nigra, in Relation to Parkinson's Disease. Biochemical and Biophysical Research Communications. 228 (2), 298-305

Cooper, CE. and Brown, GC., (1995). The Interactions between Nitric Oxide and Brain Nerve Terminals as Studied by Electron Paramagnetic Resonance. Biochemical and Biophysical Research Communications. 212 (2), 404-412

Thoresen, M., Penrice, J., Lorek, A., Cady, EB., Wylezinska, M., Kirkbride, V., Cooper, CE., Brown, GC., Edwards, AD., Wyatt, JS. and Reynolds, EOR., (1995). Mild Hypothermia after Severe Transient Hypoxia-Ischemia Ameliorates Delayed Cerebral Energy Failure in the Newborn Piglet. Pediatric Research. 37 (5), 667-670

Edwards, AD., Yue, X., Squier, MV., Thoresen, M., Cady, EB., Penrice, J., Cooper, CE., Wyatt, JS., Reynolds, EOR. and Mehmet, H., (1995). Specific Inhibition of Apoptosis after Cerebral Hypoxia-Ischemia by Moderate Post-Insult Hypothermia. Biochemical and Biophysical Research Communications. 217 (3), 1193-1199

Matcher, SJ., Elwell, CE., Cooper, CE., Cope, M. and Delpy, DT., (1995). Performance Comparison of Several Published Tissue Near-Infrared Spectroscopy Algorithms. Analytical Biochemistry. 227 (1), 54-68

Moody, AJ., Cooper, CE., Gennis, RB., Rumbley, JN. and Rich, PR., (1995). Interconversion of Fast and Slow Forms of Cytochrome bo from Escherichia coli. Biochemistry. 34 (20), 6838-6846

Cooper, CE., Green, ESR., Rice-evans, CA., Davies, MJ. and Wriggleswort, JM., (1994). A Hydrogen-Donating Monohydroxamate Scavenges Ferryl Myoglobin Radicals. Free Radical Research. 20 (4), 219-227

Mehmet, H., Yue, X., Squier, MV., Lorek, A., Cady, E., Penrice, J., Sarraf, C., Wylezinska, M., Kirkbride, V., Cooper, C., Brown, GC., Wyatt, JS., Reynolds, EOR. and Edwards, AD., (1994). Increased apoptosis in the cingulate sulcus of newborn piglets following transient hypoxia-ischaemia is related to the degree of high energy phosphate depletion during the insult. Neuroscience Letters. 181 (1-2), 121-125

Cady, EB., Lorek, A., Penrice, J., Edwards, AD., Brown, G., Owen-Reece, H., Kirkbride, V., Cooper, CE., Wyatt, JS. and Reynolds, EOR., (1994). Large increases in1H metaboliteT 2's after cerebral hypoxia-ischemia correlate with ATP depletion. Magma: Magnetic Resonance Materials in Physics, Biology, and Medicine. 2 (3), 441-444

Brown, GC. and Cooper, CE., (1994). The analysis of rate limitation within enzymes: relations between flux control coefficients of rate constants and unidirectional rates, rate constants and thermodynamic parameters of single isolated enzymes. Biochemical Journal. 300 (1), 159-164

Matcher, SJ. and Cooper, CE., (1994). Absolute quantification of deoxyhaemoglobin concentration in tissue near infrared spectroscopy. Physics in Medicine and Biology. 39 (8), 1295-1312

Tan, HM., Joannou, CL., Cooper, CE., Butler, CS., Cammack, R. and Mason, JR., (1994). The effect of ferredoxin(BED) overexpression on benzene dioxygenase activity in Pseudomonas putida ML2.. Journal of Bacteriology. 176 (9), 2507-2512

Cady, EB., Lorek, A., Penrice, J., Wylezinska, M., Cooper, CE., Brown, GC., Owen-Reece, H., Kirkbride, V., Wyatt, JS., Osmund, E. and Reynolds, R., (1994). Brain-metabolite transverse relaxation times in magnetic resonance spectroscopy increase as adenosine triphosphate depletes during secondary energy failure following acute hypoxia-ischaemia in the newborn piglet. Neuroscience Letters. 182 (2), 201-204

Cady, EB., Lorek, A., Takei, Y., Wyatt, JS., Penrice, JM., Edwards, AD., Peebles, D., Wylezinska, M., Owen-Reece, H., Kirkbride, V., Cooper, CE., Aldridge, RF., Roth, SC., Brown, G., Delpy, DT. and Reynolds, EOR., (1994). Severity of delayed (“secondary”) cerebral energy failure after acute hypoxia-ischemia is related to the time integral of acute ATP depletion. Magma: Magnetic Resonance Materials in Physics, Biology, and Medicine. 2 (3), 437-439

Brown, GC. and Cooper, CE., (1994). Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase. FEBS Letters. 356 (2-3), 295-298

Lorek, A., Takei, Y., Cady, EB., Wyatt, JS., Penrice, J., Edwards, AD., Peebles, D., Wylezinska, M., Owen-Reece, H., Kirkbride, V., Cooper, CE., Aldridge, RF., Roth, SC., Brown, G., Delpy, DT. and Reynolds, EOR., (1994). Delayed (“Secondary”) Cerebral Energy Failure after Acute Hypoxia-Ischemia in the Newborn Piglet: Continuous 48-Hour Studies by Phosphorus Magnetic Resonance Spectroscopy. Pediatric Research. 36 (6), 699-706

COOPER, CE., (1994). Ferryl iron and protein free radicals. 28 (C), 67-111

Sharpe, MA., Cooper, CE. and Wrigglesworth, JM., (1994). Transport of K+ and other cations across phospholipid membranes by nonesterified fatty acids. The Journal of Membrane Biology. 141 (1), 21-28

Brown, GC. and Cooper, CE., (1993). Control analysis applied to single enzymes: can an isolated enzyme have a unique rate-limiting step?. Biochemical Journal. 294 (1), 87-94

Cammack, R. and Cooper, CE., (1993). [12] Electron paramagnetic resonance spectroscopy of iron complexes and iron-containing proteins. Methods in Enzymology. 227 (C), 353-384

Cooper, CE., Markus, M., Seetulsingh, SP. and Wrigglesworth, JM., (1993). Kinetics of inhibition of purified and mitochondrial cytochrome c oxidase by psychosine (β-galactosylsphingosine). Biochemical Journal. 290 (1), 139-144

Cooper, CE., Markus, M., Seetulsingh, SP. and Wrigglesworth, JM., (1993). Kinetcs of inhibition of purified and mitochondrial cytochrome c oxidase by psychosine (β-galactosylsphingosine). Biochemical Journal. 290 (1), 139-144

Roberts, I., Fallon, P., Kirkham, F., Lloyd-Thomas, A., Cooper, C., Maynard, R., Elliot, M. and Edwards, AD., (1993). Estimation of cerebral blood flow with near infrared spectroscopy and indocyanine green. The Lancet. 342 (8884), 1425-1425

Cooper, CE., Jünemann, S., Ioannidis, N. and Wrigglesworth, JM., (1993). Slow (‘resting’) forms of mitochondrial cytochrome c oxidase consist of two kinetically distinct conformations of the binuclear CuBa3 centre — relevance to the mechanism of proton translocation. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1144 (2), 149-160

Dorey, C., Cooper, C., Dickson, DPE., Gibson, JF., Simpson, RJ. and Peters, TJ., (1993). Iron speciation at physiological pH in media containing ascorbate and oxygen. British Journal of Nutrition. 70 (1), 157-169

Rice-Evans, C., Green, E., Paganga, G., Cooper, C. and Wrigglesworth, J., (1993). Oxidised low density lipoproteins induce iron release from activated myoglobin. FEBS Letters. 326 (1-3), 177-182

Simpson, RJ., Cooper, CE., Raja, KB., Halliwell, B., Evans, PJ., Arouma, OI., Singh, S. and Konijn, AM., (1992). Non-transferrin-bound iron species in the serum of hypotransferrinaemic mice. Biochimica et Biophysica Acta (BBA) - General Subjects. 1156 (1), 19-26

Ioannidis, N., Cooper, CE. and Poole, RK., (1992). Spectroscopic studies on an oxygen-binding haemoglobin-like flavohaemoprotein from Escherichia coli. Biochemical Journal. 288 (2), 649-655

Cooper, CE. and Odell, E., (1992). Interaction of human myeloperoxidase with nitrite. FEBS Letters. 314 (1), 58-60

Cooper, CE. and Salerno, JC., (1992). Characterization of a novel g' = 2.95 EPR signal from the binuclear center of mitochondrial cytochrome c oxidase. Journal of Biological Chemistry. 267 (1), 280-285

Cooper, CE., Nicholls, P. and Freedman, JA., (1991). Cytochrome c oxidase: structure, function, and membrane topology of the polypeptide subunits. Biochemistry and Cell Biology. 69 (9), 586-607

Moody, AJ., Cooper, CE. and Rich, PR., (1991). Characterisation of ‘fast’ and ‘slow’ forms of bovine heart cytochrome-c oxidase. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1059 (2), 189-207

Cooper, CE., (1990). The steady-state kinetics of cytochrome c oxidation by cytochrome oxidase. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1017 (3), 187-203

Wrigglesworth, JM., Cooper, CE., Sharpe, MA. and Nicholls, P., (1990). The proteoliposomal steady state. Effect of size, capacitance and membrane permeability on cytochrome-oxidase-induced ion gradients. Biochemical Journal. 270 (1), 109-118

Cooper, CE. and Nicholls, P., (1990). Structure and vectorial properties of proteoliposomes containing cytochrome oxidase in the submitochondrial orientation. Biochemistry. 29 (16), 3865-3871

Cooper, CE., Bruce, D. and Nicholls, P., (1990). Use of Oxonol V as a probe of membrane potential in proteoliposomes containing cytochrome oxidase in the submitochondrial orientation. Biochemistry. 29 (16), 3859-3865

Cooper, CE., Wrigglesworth, JM. and Nicholls, P., (1990). The mechanism of potassium movement across the liposomal membrane. Biochemical and Biophysical Research Communications. 173 (3), 1008-1012

Nicholls, P., Cooper, CE. and Wrigglesworth, JM., (1990). Control of proteoliposomal cytochrome c oxidase: the overall reaction. Biochemistry and Cell Biology. 68 (9), 1128-1134

Nicholls, P. and Cooper, CE., (1989). Modulation of cytochrome oxidase kinetics by indirect antibody action. FEBS Letters. 250 (2), 453-458

Nicholls, P., Cooper, CE., Leece, B., Freedman, JA. and Chan, SH., (1988). Antibodies as probes of cytochrome oxidase structure and function.. Progress in clinical and biological research. 274, 637-651

Nicholls, P., Cooper, CE., Freedman, JA. and Leece, BD., (1988). Effects of antibodies to intact cytochrome-c oxidase and its subunit V on the enzymatic activity. Biochemistry and Cell Biology. 66 (11), 1218-1225

Freedman, JA., Leece, B., Cooper, CE., Nicholls, P. and Chan, SHP., (1988). Effects of subunit V antibodies on the topology of the subunit and the activity of beef heart cytochrome-c oxidase. Biochemistry and Cell Biology. 66 (11), 1210-1217

Cooper, CE. and Nicholls, P., (1987). Activity of proteoliposomes containing cytochrome oxidase in the submitochondrial orientation. FEBS Letters. 223 (1), 155-160

Books (2)

Cooper, CE., (2016). Blood: A Very Short Introduction. Oxford University Press. 9780199581450

Cooper, C., (2012). Run, Swim, Throw, Cheat The Science Behind Drugs in Sport. Oxford University Press. 0199581460. 9780199581467

Book chapters (3)

Jones, B. and Cooper, CE., (2018). Near Infrared Spectroscopy (NIRS) observation of vastus lateralis (muscle) and prefrontal cortex (brain) tissue oxygenation during synchronised swimming routines in elite athletes. In: Oxygen Transport to Tissue XL. Editors: Thews, O., LaManna, J. and Harrison, D., . Springer. 111- 117. 978-3-319-91285-1

Silkstone, GGA., Simons, M., Rajagopal, BS., Shaik, T., Reeder, BJ. and Cooper, CE., (2018). Novel Redox Active Tyrosine Mutations Enhance the Regeneration of Functional Oxyhemoglobin from Methemoglobin: Implications for Design of Blood Substitutes.. In: Oxygen Transport to Tissue XL. Editors: Thews, O., LaManna, J. and Harrison, D., . Springer. 221- 225. 978-3-319-91285-1

Silkstone, RS., Silkstone, G., Baath, JA., Rajagopal, BS., Nicholls, P., Reeder, BJ., Ronda, L., Bulow, L. and Cooper, CE., (2016). The ?Lys66Tyr Variant of Human Hemoglobin as a Component of a Blood Substitute. In: Oxygen Transport to Tissue XXXVII. Editors: Elwell, CE., Leung, TS. and Harrison, DK., . Springer. 455- 460

Conferences (44)

Moroz, T., Hapuarachchi, T., Bainbridge, A., Price, D., Cady, E., Baer, E., Broad, K., Ezzati, M., Thomas, D., Golay, X., Robertson, NJ., Cooper, CE. and Tachtsidis, I., (2013). Modelling Blood Flow and Metabolism in the Piglet Brain During Hypoxia-Ischaemia: Simulating Brain Energetics

Jones, B., Hesford, CM. and Cooper, CE., (2013). The use of portable NIRS to measure muscle oxygenation and haemodynamics during a repeated sprint running test

Rong, Z. and Cooper, CE., (2013). Modeling hemoglobin nitrite reductase activity as a mechanism of hypoxic vasodilation?

Moroz, T., Hapuarachchi, T., Bainbridge, A., Price, D., Cady, E., Baer, E., Tachtsidis, I., Broad, K., Ezzati, M., Robertson, NJ., Thomas, D., Golay, X. and Cooper, CE., (2013). Modelling blood flow and metabolism in the piglet brain during hypoxia-ischaemia: Simulating brain energetics

Hesford, CM., Laing, S. and Cooper, CE., (2013). Using portable NIRS to compare arm and leg muscle oxygenation during roller skiing in biathletes: A case study

Rong, Z., Banaji, M., Moroz, T. and Cooper, CE., (2013). Can mitochondrial cytochrome oxidase mediate hypoxic vasodilation via nitric oxide metabolism?

Hesford, C., Cardinale, M., Laing, S. and Cooper, CE., (2013). NIRS measurements with elite speed skaters: Comparison between the ice rink and the laboratory

Nicholls, P., Mason, MG. and Cooper, CE., (2012). Cytochrome c oxidase heme and Cu centres: Redox and spectral interactions

Moroz, T., Banaji, M., Tisdall, M., Cooper, CE., Elwell, CE. and Tachtsidis, I., (2012). Development of a Model to Aid NIRS Data Interpretation: Results from a Hypercapnia Study in Healthy Adults

Ghosh, A., Tachtsidis, I., Kolyva, C., Cooper, CE., Smith, M. and Elwell, CE., (2012). Use of a Hybrid Optical Spectrometer for the Measurement of Changes in Oxidized Cytochrome c Oxidase Concentration and Tissue Scattering During Functional Activation

Gao, L., ElwellElwell, CE., Kohl-Bareis, M., Gramer, M., Cooper, CE., Leung, TS. and Tachtsidis, I., (2011). Effects of Assuming Constant Optical Scattering on Haemoglobin Concentration Measurements Using NIRS during a Valsalva Manoeuvre

Nicholls, P., Mason, MG. and Cooper, CE., (2010). Cytochrome c Oxidase CuA and Heme A: Redox Equilibrium and Interactions

Hesford, C., Cooper, CE. and Cardinale, M., (2010). Near Infrared Spectroscopy Measurements Of Muscle Metabolism In Elite Short-track Speed Skaters During On-ice Race Simulation

Tachtsidis, I., Gao, L., Leung, TS., Kohl-Bareis, M., Cooper, CE. and Elwell, CE., (2010). A Hybrid Multi-Distance Phase and Broadband Spatially Resolved Spectrometer and Algorithm for Resolving Absolute Concentrations of Chromophores in the Near-Infrared Light Spectrum

Leung, TS., Wittekind, A., Binzoni, T., Beneke, R., Cooper, CE. and Elwell, CE., (2010). Muscle Oxygen Saturation Measured Using “Cyclic NIR Signals” During Exercise

Reeder, BJ., Svistunenko, DA., Cooper, CE. and Wilson, MT., (2009). Engineering Electron Transfer Pathways in Myoglobin and Hemoglobin: A Route to Detoxify Blood Substitutes?

Tachtsidis, I., Tisdall, MM., Leung, TS., Pritchard, C., Cooper, CE., Smith, M. and Elwell, CE., (2009). Relationship Between Brain Tissue Haemodynamics, Oxygenation And Metabolism In The Healthy Human Adult Brain During Hyperoxia And Hypercapnea

Mason, MG., Nichols, P. and Cooper, CE., (2008). S11. 10 Steady state redox interactions of cytochrome c oxidase

Nicholls, P. and Cooper, CE., (2008). S13.33 Does cytochrome c oxidase pump protons in the controlled state?

Tachtsidis, I., Leung, TS., Tahir, B., Elwell, CE., Kohl-Bareis, M., Gramer, M. and Cooper, CE., (2008). A Hybrid Multi-Distance Phase and Broadband Spatially Resolved Algorithm for Resolving Absolute Concentrations of Chromophores in the Near-Infrared Light Spectrum: Results from Studies in Dynamic Phantoms

Leung, TS., Tachtsidis, I., Elwell, CE., Tisdall, M., Pritchard, C., Smith, M. and Cooper, C., (2008). Investigating Cross-talk in Cytochrome C Oxidase Concentration Quantification using Near Infrared Spectroscopy in a Two-layered Model

Reeder, BJ., Nilson, M., Bulow, L., Cooper, CE. and Wilson, MT., (2007). Modulating electron transfer pathways in hemoglobin

Myers, DE., Cooper, CE., Beilman, GJ., Mowlem, JD., Anderson, LD., Seifert, RP. and Ortner, JP., (2006). A Wide Gap Second Derivative NIR Spectroscopic Method for Measuring Tissue Hemoglobin Oxygen Saturation

Vollaard, NB., Shearman, JP. and Cooper, CE., (2004). The oxidative stress response to exercise is unchanged after tapering, but antioxidant defenses are improved

Nicholls, P., Cooper, CE. and Reynolds, CV., (2001). Tyrosinyl nitration by peroxidase & other hemoproteins

Davies, NA., Hodges, SJ., Mookerjee, RP., Sen, S., Cooper, CE. and Jalan, R., (2001). Evidence of significant oxidative stress and free radical activity in alcoholic hepatitis

Dunne, J., Svistunenko, DA., Alayash, AI., Wilson, MT. and Cooper, CE., (1999). Increased free radical formation by hemoglobin based oxygen carriers.

Davies, NA., Wyatt, JS. and Cooper, CE., (1999). Use of Elecron Paramagnetic Resonance spectroscopy to determine nitric oxide overproduction during hypoxic-ischaemic damage to the neonatal brain.

Dunne, J., Svistunenko, DA., Alayash, AI., Wilson, MT. and Cooper, CE., (1999). Reactions of Cross-Linked Methaemoglobins with Hydrogen Peroxide

A. Svistunenko, D., A. Davies, N., T. Wilson, M., P. Stidwill, R., Singer, M. and E. Cooper, C., (1997). Free radical in blood: a measure of haemoglobin autoxidation in vivo? †

Cooper, C., Sharpe, M., Elwell, C., Springett, R., Penrice, J., Tyszczuk, L., Amess, P., Wyatt, J., Quaresima, V. and Delpy, D., (1997). The Cytochrome Oxidase Redox State in Vivo

TORRES, J., COOPER, CC. and WILSON, MT., (1996). Possible interaction of nitric oxide with the ferryl intermediate of cytochrome c oxidase

Sharpe, M., Perin, I., Nicholls, P. and Cooper, C., (1996). Free fatty acids as modulators of cytochrome c oxidase activity

Cooper, CE., Ioannidis, N., D'mello, R. and Poole, RK., (1994). Haem, flavin and oxygen interactions in Hmp, a flavohaemoglobin from Escherichia coli

Elwell, CE., Cope, M., Kirkby, D., Owen-Reece, H., Cooper, CE., Reynolds, EOR. and Delpy, DT., (1994). An Automated System for the Measurement of the Response of Cerebral Blood Volume and Cerebral Blood Flow to Changes in Arterial Carbon Dioxide Tension Using Near Infrared Spectroscopy

Cooper, CE., Matcher, SJ., Wyatt, JS., Cope, M., Brown, GC., Nemoto, EM. and Delpy, DT., (1994). Near-infrared spectroscopy of the brain: relevance to cytochrome oxidase bioenergetics

(1994). Relation between cerebral nucleotide triphosphate depletion due to acute hypoxiaischaemia, and secondary energy failure in the newborn piglet

COOPER, CE., IOANNIDIS, N., DMELLO, R. and POOLE, RK., (1994). HEME, FLAVIN AND OXYGEN INTERACTIONS IN HMP, A FLAVOHAEMOGLOBIN FROM ESCHERICHIA-COLI

Wrigglesworth, JM., Sharpe, MA. and Cooper, CE., (1993). Regulation of electron flux through cytochrome c oxidase: pH, ΔpH and fatty acids

Green, ESR., Cooper, CE., Davies, MJ. and Rice-Evans, C., (1993). Antioxidant drugs and the inhibition of low-density lipoprotein oxidation

COOPER, CE. and ODELL, E., (1992). EPR differences between human myeloperoxidase isoenzymes

GREEN, ES., COOPER, C., WRIGGLESWORTH, J. and RICE-EVANS, C., (1992). A NOVEL HYDROGEN-DONATING DRUG SUPPRESSES HAEM DAMAGE FROM MYOGLOBIN MEDIATED BY OXIDISED LOW DENSITY LIPOPROTEINS

Sharpe, MA., Cooper, CE. and Wrigglesworth, JM., (1991). The Effect of Membrane Potential on the Protonophoric Action of Oleic Acid

COOPER, CE., MOODY, AJ., RICH, PR., WRIGGLESWORTH, JM. and IOANNIDIS, N., (1991). The cytochrome oxidase g'=12 EPR signal

Grants and funding

2013

Creating an Effective and Non Toxic Blood Substitute

Biotechnology & Biology Science Res.Council

Engineering a new generation of blood substitutes

Medical Research Council

2012

Quantification of the Effect of Adipose Tissue Thickness

Artinis Medical Systems B.V.

Blood Substitutes Project

Iceni Seedcorn Fund

Creating an effective and non toxic blood substitute

Biotechnology & Biology Science Res.Council

2010

Novel Methods to measure brain and oxygen metabolism

The Royal Society

Gas signalling and biological energy

Leverhulme Trust

Heme blockers: Reducing the toxicity of extracellular

Biotechnology & Biology Science Res.Council

Integrating monitoring & modelling for real-time tracking

Wellcome Trust

2009

Non-Invasive Multi Modal Cerebral Monitoring

Medical Research Council

Haem Therapeutics Pathfinder

Iceni Seedcorn Fund

2008

Artificial Blood

Biotechnology & Biology Science Res.Council

ISIS - Free Radical Chemistry of Haemoglobin

Biotechnology & Biology Science Res.Council

The Magic Of Blood: Shining Light On Chemistry, Physics & Bi

Engineering & Physical Sciences Res.Council

OMI Studentship - Catherine Hesford

Olympic Medical Institute

Contact

ccooper@essex.ac.uk
+44 (0) 1206 876179

Location:

ESA.3.25, Colchester Campus