BS983-7-SP-CO:
Protein Technologies and Proteomics

The details
2021/22
Life Sciences (School of)
Colchester Campus
Spring
Postgraduate: Level 7
Current
Monday 17 January 2022
Friday 25 March 2022
15
31 March 2021

 

Requisites for this module
(none)
(none)
(none)
(none)

 

(none)

Key module for

MSC C56012 Biotechnology,
MSC C74112 Molecular Medicine,
MSC C13312 Cancer Biology,
MSCIC098 Biochemistry and Biotechnology (Including Year Abroad),
MSCIC099 Biochemistry and Biotechnology (Including Placement Year),
MSCICZ99 Biochemistry and Biotechnology

Module description

This module describes the basic features and properties of proteins and their relation to protein function. It provides hands on experience in the production, isolation, purification and characterisation of proteins with biotechnological potential.

The relationship of protein structure to function is examined in light of the mechanisms of enzyme catalysis, signal transduction and other important biological processes. The techniques used in protein purification are described and the laboratory classes provide experience in protein purification and analysis. In addition, you will obtain theoretical and practical experience of obtaining and analysing proteomic data.

Module aims

The module aims to provide students with the necessary knowledge, skills and hand-on experience in protein production, purification and analysis.

Module learning outcomes

In order to pass this module the student will need to be able to:

1. Explain the factors that determine protein structure and function;
2. Be able to discuss the different levels of protein structural organization;
3. Explain how proteins are synthesized in the cell and how their function is regulated by alternative splicing and post-translational modification;
4. Discuss protein targeting in prokaryotic and eukaryotic cells;
5. Describe the range of techniques used in protein analysis;
6. Discuss the methods of production of recombinant proteins;
7. Describe how different types of chromatography can be combined to achieve better protein purification;
8. Describe gel electrophoresis and its application for protein analysis;
9. Understand the principles of proteomics and its applications;
10. Demonstrate practical competence in key protein purification and analysis techniques;
11. Develop a range of key skills including information acquisition from web-based and library sources, self-directed learning, numeracy, writing and presentation of scientific reports.

Module information

No additional information available.

Learning and teaching methods

Lectures - 12 h Practicals - 6 x 3 = 18 h

Bibliography

This module does not appear to have a published bibliography for this year.

Assessment items, weightings and deadlines

Coursework / exam Description Deadline Coursework weighting
Coursework   SPF Report    45% 
Coursework   Data Analysis Report    30% 
Practical   Multiple Choice Tests    25% 

Exam format definitions

  • Remote, open book: Your exam will take place remotely via an online learning platform. You may refer to any physical or electronic materials during the exam.
  • In-person, open book: Your exam will take place on campus under invigilation. You may refer to any physical materials such as paper study notes or a textbook during the exam. Electronic devices may not be used in the exam.
  • In-person, open book (restricted): The exam will take place on campus under invigilation. You may refer only to specific physical materials such as a named textbook during the exam. Permitted materials will be specified by your department. Electronic devices may not be used in the exam.
  • In-person, closed book: The exam will take place on campus under invigilation. You may not refer to any physical materials or electronic devices during the exam. There may be times when a paper dictionary, for example, may be permitted in an otherwise closed book exam. Any exceptions will be specified by your department.

Your department will provide further guidance before your exams.

Overall assessment

Coursework Exam
100% 0%

Reassessment

Coursework Exam
100% 0%
Module supervisor and teaching staff
Dr Metodi Metodiev, email: mmetod@essex.ac.uk.
Dr Metodi Metodiev
School Graduate Office, email: bsgradtaught (Non essex users should add @essex.ac.uk to create a full email address)

 

Availability
Yes
No
No

External examiner

Dr Lakjaya Buluwela
Imperial College of Science Technology and Medicine
Reader in Cancer Medicine
Dr Emma Denham
University of Bath
Senior Lecturer in Microbiology
Resources
Available via Moodle
Of 650 hours, 11 (1.7%) hours available to students:
639 hours not recorded due to service coverage or fault;
0 hours not recorded due to opt-out by lecturer(s).

 

Further information
Life Sciences (School of)

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