BS983-7-AP-CO:
Protein Technologies
2020/21
Life Sciences (School of)
Colchester Campus
Autumn & Spring
Postgraduate: Level 7
Current
Thursday 08 October 2020
Friday 26 March 2021
15
22 January 2021
Requisites for this module
(none)
(none)
(none)
(none)
(none)
MSC C56012 Biotechnology,
MSC C74112 Molecular Medicine,
MSC C13312 Cancer Biology,
MSCIC098 Biochemistry and Biotechnology (Including Year Abroad),
MSCIC099 Biochemistry and Biotechnology (Including Placement Year),
MSCICZ99 Biochemistry and Biotechnology
This module describes the basic features and properties of proteins and their relation to protein function. It provides hands on experience in the production, isolation, purification and characterisation of proteins with biotechnological potential.
The relationship of protein structure to function is examined in light of the mechanisms of enzyme catalysis, signal transduction and other important biological processes. The techniques used in protein purification are described and the laboratory classes provide experience in protein purification and analysis. In addition, you will obtain theoretical and practical experience of obtaining and analysing proteomic data.
The module aims to provide students with the necessary knowledge, skills and hand-on experience in protein production, purification and analysis.
Learning Outcomes
In order to pass this module the student will need to be able to:
1. Explain the factors that determine protein structure and function;
2. Be able to discuss the different levels of protein structural organization;
3. Explain how proteins are synthesized in the cell and how their function is regulated by alternative splicing and post-translational modification;
4. Discuss protein targeting in prokaryotic and eukaryotic cells;
5. Describe the range of techniques used in protein analysis;
6. Discuss the methods of production of recombinant proteins;
7. Describe how different types of chromatography can be combined to achieve better protein purification;
8. Describe gel electrophoresis and its application for protein analysis;
9. Understand the principles of proteomics and its applications;
10. Demonstrate practical competence in key protein purification and analysis techniques;
11. Develop a range of key skills including information acquisition from web-based and library sources, self-directed learning, numeracy, writing and presentation of scientific reports.
No additional information available.
Lectures - 12 h
Practicals - 6 x 3 = 18 h
- Petsko, Gregory A.; Ringe, Dagmar. (2008) Protein Structure and Function, Oxford: Oxford University Press.
- Nelson, David L.; Lehninger, Albert L.; Cox, Michael M. (2017) Lehninger Principles of Biochemistry, Basingstoke: Macmillan Higher Education.
The above list is indicative of the essential reading for the course. The library makes provision for all reading list items, with digital provision where possible, and these resources are shared between students. Further reading can be obtained from this module's reading list.
Assessment items, weightings and deadlines
| Coursework / exam |
Description |
Deadline |
Coursework weighting |
| Coursework |
SPF Report |
|
45% |
| Coursework |
Data Analysis Report |
|
30% |
| Practical |
Multiple Choice Tests |
|
25% |
Exam format definitions
- Remote, open book: Your exam will take place remotely via an online learning platform. You may refer to any physical or electronic materials during the exam.
- In-person, open book: Your exam will take place on campus under invigilation. You may refer to any physical materials such as paper study notes or a textbook during the exam. Electronic devices may not be used in the exam.
- In-person, open book (restricted): The exam will take place on campus under invigilation. You may refer only to specific physical materials such as a named textbook during the exam. Permitted materials will be specified by your department. Electronic devices may not be used in the exam.
- In-person, closed book: The exam will take place on campus under invigilation. You may not refer to any physical materials or electronic devices during the exam. There may be times when a paper dictionary,
for example, may be permitted in an otherwise closed book exam. Any exceptions will be specified by your department.
Your department will provide further guidance before your exams.
Overall assessment
Reassessment
Module supervisor and teaching staff
Dr Metodi Metodiev, email: mmetod@essex.ac.uk.
Dr Metodi Metodiev
School Graduate Office, email: bsgradtaught (Non essex users should add @essex.ac.uk to create a full email address)
No
No
No
Dr Lakjaya Buluwela
Imperial College of Science Technology and Medicine
Reader in Cancer Medicine
Prof Mark Wheatley
University of Birmingham
Chair of Biochemical Pharmacology
Dr Emma Denham
University of Bath
Senior Lecturer in Microbiology
Available via Moodle
Of 590 hours, 0 (0%) hours available to students:
590 hours not recorded due to service coverage or fault;
0 hours not recorded due to opt-out by lecturer(s).
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