Dr Michelle Simons

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Email
msimons@essex.ac.uk -
Location
Colchester Campus
Publications
Journal articles (3)
Cooper, CE., Bird, M., Sheng, X., Choi, J-W., Silkstone, GGA., Simons, M., Syrett, N., Piano, R., Ronda, L., Bettati, S., Paredi, G., Mozzarelli, A. and Reeder, BJ., (2021). Stability of Maleimide-PEG and Mono-Sulfone-PEG Conjugation to a Novel Engineered Cysteine in the Human Hemoglobin Alpha Subunit. Frontiers in Chemistry. 9, 707797-
Cooper, CE., Silkstone, GGA., Simons, M., Gretton, S., Rajagopal, BS., Allen-Baume, V., Syrett, N., Shaik, T., Popa, G., Sheng, X., Bird, M., Choi, J-W., Piano, R., Ronda, L., Bettati, S., Paredi, G., Mozzarelli, A. and Reeder, BJ., (2020). Engineering hemoglobin to enable homogenous PEGylation without modifying protein functionality. Biomaterials Science. 8 (14), 3896-3906
Cooper, CE., Silkstone, GGA., Simons, M., Rajagopal, B., Syrett, N., Shaik, T., Gretton, S., Welbourn, E., Bülow, L., Eriksson, NL., Ronda, L., Mozzarelli, A., Eke, A., Mathe, D. and Reeder, BJ., (2019). Engineering tyrosine residues into hemoglobin enhances heme reduction, decreases oxidative stress and increases vascular retention of a hemoglobin based blood substitute. Free Radical Biology and Medicine. 134, 106-118