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University of Essex homepage Events Insights into Human Common Diseases
Event

Insights into Human Common Diseases via the Impact of Ageing & Genomic Variation on the DNA methylome

  • Thu 20 Oct 22

    13:00 - 14:00

  • Colchester Campus

    STEM 3.1

  • Event speaker

    Christopher Graeme Bell

  • Event type

    Lectures, talks and seminars

  • Event organiser

    Life Sciences, School of

  • Contact details

    Dr Patrick Varga Weisz

Our rapidly improving ability to analyse the epigenome – the chemical modifications and packaging of the genome that indicate cell-type specific activity – brings powerful and novel insights into disease mechanisms.

This includes how disease-related genetic variation impacts on the epigenome, and a robust biomarker ability to capture environmental exposures. Also, the epigenome dramatically deteriorates with age.

These ageing changes may be instrumental in chronic ageing-related diseases, and we present new findings of their interplay with increasingly complex tRNA biology.

Speaker

Christopher Bell is based in the William Harvey Research Institute, Charterhouse Square, Queen Mary University of London. He gained his PhD in Human Genomics from Imperial College London investigating genetic susceptibility to Type 2 Diabetes and Obesity. His Postdoctoral training, in Human Epigenomics, was undertaken at UCL with Prof Stephan Beck, where they pioneered integrative analyses of the DNA methylome within common disease-associated loci.

His research group is focused on using epigenomic analysis to mechanistically understand the pathophysiology of human common disease, with a specific focus on metabolic and chronic ageing-related disorders. This work involves large-scale computational, statistical, and functional integration of multi-omic human datasets.

How to attend

This seminar is being held in person in STEM 3.1 (STEM Centre on Square 1, Colchester campus). You can also watch via Zoom (meeting ID: 916 2270 2239)

If you have any queries about this seminar please email Dr Patrick Varga Weisz (patrick.varga-weisz@essex.ac.uk).

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