Our ageing work focuses on changes in the nucleus that accompany ageing and senescence, encompassing genetic change, epigenetic remodelling and transcriptional de-repression.
We ask whether these drive ageing or result from an underlying ageing process, whether these outcomes are independent, and how the rate of each depends on diet and the environment.
A particular interest is whether aspects of the ageing process evolved under positive selection, and if so whether there are regulatory mechanisms for ageing.
Speaker
Dr Jonathan Houseley is a Wellcome Trust Senior Research Fellow at the Babraham Institute, where he is studying the mechanisms that lead to genetic and epigenetic change. He is particularly interested in the ability of cells to alter their heritable genomes in response to particular environmental conditions, and therefore to rapidly adapt to changing environments.
Jonathan holds a PhD from the University of Glasgow, where he worked on a Drosophila model of myotonic dystrophy.
How to attend
This seminar is being held in person in STEM 3.1 (STEM Centre on Square 1, Colchester campus).
If you have any queries about this seminar please email Dr Patrick Varga-Weisz (patrick.varga-weisz@essex.ac.uk).