Labs and facilities
Our dedicated Centre for Brain Science houses many of our labs, and we also have additional facilities available for a wide
range of psychological studies.
Centre for Brain Science
Our Centre for Brain Science (CBS) opened in 2009 and is purpose-built to house state-of-the-art equipment that allows staff to
directly measure and modulate brain activity, as well as a range of equipment to measure eye movements and various indices
of physiological response.
The CBS won a Sustainable Developments award in the 2008 Colchester 2020 and RIBA Architectural Awards. It is one of the most
environmentally sustainable buildings at our Colchester Campus.
Transcranial magnetic stimulation (TMS)
Neuromodulation, in the form of transcranial magnetic stimulation (TMS) and transcranial direct/alternating current stimulation
(tD/ACS) is a means of non-invasively but directly stimulating the brain. TMS has many guises. For example, single pulses can be
used to briefly and transiently disrupt information processing in the underlying cortex or to measure the excitability of the
corticospinal tract. Paired-pulses can be used to examine inhibitory and excitatory circuits in the brain. Repetitive pulses
(rTMS) and tD/ACS can be used to alter the excitability of the cortex and have many possible clinical applications (eg in the
treatment of depression, tinnitus, auditory hallucinations, epilepsy and many others). In the CBS, TMS is currently used in the
- to stimulate motor evoked potentials (MEPs) as an index of mirror neuron system activation
- to modulate EEG oscillations (particularly in the alpha bandwidth) in order to a) explore the functional significance of such
oscillatory activity and b) to examine possible future clinical applications
- to investigate the role of the dorsal stream in near/far visual processing
The CBS is equipped with two of the latest Magstim Transcranial Magnetic Stimulation (TMS) systems – the 2002/Bistim2 and the
Rapid2. This provides the capability for running a variety of TMS protocols including: single pulse, paired-pulse, repetitive
trains (rTMS) and dual coil approaches (e.g. transcallosal inhibition). We also have the Brainsight2, a stereotactic image guidance
system that facilitates the positioning of transcranial magnetic stimulator coils over a subject's brain. Electrical stimulation
of the brain is also possible using the latest Magstim Eldith Transcranial Direct Current Stimulator Plus. With this device,
transcranial direct current stimulation (tDCS) is possible in either continuous or pulsed modes. The combination of neuromodulation
with our other psychophysiological tools (eg EEG, NIRS) opens an exciting new avenue for research in cognitive neuroscience.
EEG is a completely non-invasive method of recording cortical activity or "brain-waves". Here at the CBS, EEG research is carried
out in a number of areas. We examine experimentally driven changes in the EEG to gain insight into cortical mechanisms associated with
areas of interest that include:
- mirror neuron systems
- attentional bias and control
- emotional prosody in language processing
- the relationship between cortical and autonomic control
- multimodal sensory processing and perception
Also, at a fundamental level, we are constantly seeking to explore the functional significance of the EEG ("what do these brain-waves
The CBS is equipped with three state-of-the-art EEG systems:
- a 256 channel EGI Geodesic EEG System 300 with geodesic nets appropriate for both clinical and developmental studies
- a 128 channel Neuroscan Synamps II system (capable of being broken down into two 64 channel systems)
- a 64 channel Advanced Neuro Technology (ANT) ASA-lab EEG/ERP system
Both ANT and Neuroscan systems are compatible with TMS.
Near infra-red spectroscopy (NIRS)
NIRS is a method of recording changes in blood oxygen levels. In terms of the brain, it has been dubbed DIY-fMRI, in that like fMRI,
it also measures changes in oxygenated and de-oxygenated haemoglobin (although by very different means). To explain briefly, when an
area of the brain is active, it uses oxygen to fuel this activity. This is immediately followed by an increase in blood flow to that
area, carrying fresh oxygen in the form of oxygenated haemoglobin. NIRS works by shining near infrared light into tissue and measuring
the amount that is reflected back. Changes in the concentration of oxygenated and de-oxygenated haemoglobin affect this reflection.
NIRS records these changes and in so doing provides an indirect measure of cortical activity. The department has two 24-channels Artinis
Oxymon III near infrared systems capable of being configured into one 48-channels system when required.
Virtual reality suite
The CBS has two virtual reality suites equipped with a Virtualis VR system. It intergrates InterSense head, hand and eye-tracking
capabilities with an NVIS MX90 head mounted display with a 1280 x 1024 resolution and 90 degree FOV. Environments and characters are
built using Visage Technologies software.
In our Babylab, we study the development of perceptual and cognitive abilities in infants.
The lab is equipped with non-invasive cutting-edge technology to help us better understand how young children perceive and act on the world around them.
We use an eye-tracking device to gather data about their visual preferences, and a baby-friendly EEG system to record the natural brain activity in response to different tasks.
Other specialist labs and facilities
- Observation suite with one-way mirror, testing room and observation room equipped with video recording facilities.
- Visual perception lab with head mounted eye-tracker; telespectroradiometer; intuitive colorimeter; precision tints;
optometric trial lenses; monochromator; photometers and a range of clinical optometrictest equipment.
- Cognitive perception lab with ASL variable-speed, remote pan/tilt optics eye-tracker, with video head tracking and
Cambridge Research Systems VISaGe system for precision colour stimulus presentation. Includes VISaGe stimulus generator, 22" precision
colour monitor, for threshold measurement and calibration facilities for both screen presented and paper stimuli. Two portable touch
screen computers with writing tablets.
- Two psychoacoustic hearing labs, with a total of four high spec double-walled soundproof booths, with OAE recording
- Group testing suite consisting of multiple neighbouring cubicles, whose computers can be interlinked to allow
real-time group behavioural studies.