BS983-7-SP-CO:
Protein Technologies and Proteomics
2023/24
Life Sciences (School of)
Colchester Campus
Spring
Postgraduate: Level 7
Current
Monday 15 January 2024
Friday 22 March 2024
15
16 February 2024
Requisites for this module
(none)
(none)
(none)
(none)
(none)
MSC C56012 Biotechnology,
MSC C74112 Molecular Medicine,
MSC C13312 Cancer Biology,
MSCIB099 Biomedical Science,
MSCIBA99 Biomedical Science (Including Placement Year),
MSCIBB99 Biomedical Science (Including Year Abroad),
MSCIC098 Biochemistry and Biotechnology (Including Year Abroad),
MSCIC099 Biochemistry and Biotechnology (Including Placement Year),
MSCICZ99 Biochemistry and Biotechnology,
MSCIC559 Microbiology and Biotechnology
This module describes the basic features and properties of proteins and their relation to protein function.
The module provides hands on experience in the production, isolation, purification and characterisation of proteins with biotechnological potential.
The aim of this module is:
- To provide students with the necessary knowledge, skills and hand-on experience in protein production, purification and analysis.
By the end of this module, students will be expected to be able to:
- Explain the factors that determine protein structure and function.
- Be able to discuss the different levels of protein structural organization.
- Explain how proteins are synthesized in the cell and how their function is regulated by alternative splicing and post-translational modification.
- Discuss protein targeting in prokaryotic and eukaryotic cells.
- Describe the range of techniques used in protein analysis.
- Discuss the methods of production of recombinant proteins.
- Describe how different types of chromatography can be combined to achieve better protein purification.
- Describe gel electrophoresis and its application for protein analysis.
- Understand the principles of proteomics and its applications.
- Demonstrate practical competence in key protein purification and analysis techniques.
- Develop a range of key skills including information acquisition from web-based and library sources, self-directed learning, numeracy, writing and presentation of scientific reports.
The relationship of protein structure to function is examined in light of the mechanisms of enzyme catalysis, signal transduction and other important biological processes. The techniques used in protein purification are described and the laboratory classes provide experience in protein purification and analysis. In addition, you will obtain theoretical and practical experience of obtaining and analysing proteomic data.
This module will be delivered via:
- One 1-hour lecture per week.
- Six 3-hour practicals.
The above list is indicative of the essential reading for the course.
The library makes provision for all reading list items, with digital provision where possible, and these resources are shared between students.
Further reading can be obtained from this module's
reading list.
Assessment items, weightings and deadlines
| Coursework / exam |
Description |
Deadline |
Coursework weighting |
| Coursework |
MCQ1 |
|
6.25% |
| Coursework |
MCQ 2 |
|
6.25% |
| Coursework |
MCQ 3 |
|
6.25% |
| Coursework |
MCQ 4 |
|
6.25% |
| Coursework |
Data Analysis Report |
|
40% |
| Practical |
Moodle Quiz - Deadline Only - Do Not Submit on FASER |
|
35% |
Exam format definitions
- Remote, open book: Your exam will take place remotely via an online learning platform. You may refer to any physical or electronic materials during the exam.
- In-person, open book: Your exam will take place on campus under invigilation. You may refer to any physical materials such as paper study notes or a textbook during the exam. Electronic devices may not be used in the exam.
- In-person, open book (restricted): The exam will take place on campus under invigilation. You may refer only to specific physical materials such as a named textbook during the exam. Permitted materials will be specified by your department. Electronic devices may not be used in the exam.
- In-person, closed book: The exam will take place on campus under invigilation. You may not refer to any physical materials or electronic devices during the exam. There may be times when a paper dictionary,
for example, may be permitted in an otherwise closed book exam. Any exceptions will be specified by your department.
Your department will provide further guidance before your exams.
Overall assessment
Reassessment
Module supervisor and teaching staff
Prof Vassiliy Bavro, email: v.bavro@essex.ac.uk.
Prof Vass Bavro, Dr James Birrell, Dr Philip Reeves, Dr Metodi Metodiev
School Graduate Office, email: bsgradtaught (Non essex users should add @essex.ac.uk to create a full email address)
Yes
No
No
Dr Lakjaya Buluwela
Imperial College of Science Technology and Medicine
Reader in Cancer Medicine
Dr Emma Denham
University of Bath
Senior Lecturer in Microbiology
Available via Moodle
Of 90 hours, 18 (20%) hours available to students:
72 hours not recorded due to service coverage or fault;
0 hours not recorded due to opt-out by lecturer(s), module, or event type.
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The University will endeavour to keep such changes to a minimum, and will also keep students informed appropriately by updating our programme specifications and module directory.
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